| Type | Description |
|---|---|
| Definition | glutamate ionotropic receptor kainate type subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 10:51:00 | Neto1 and Neto2 differentially regulate GluK2 fast gating kinetics | 31628192 |
| 2020-01-18 11:18:00 | GluK2 overexpression promoted dendritic growth in pyramidal cells and interneurons. | 30421168 |
| 2019-11-02 10:42:00 | that activity-dependent regulation of ADAR2 proteostasis and GluK2 Q/R editing are key determinants of kainate receptors | 30559217 |
| 2019-03-02 10:17:00 | Results showed that the S-nitrosylation of GluK2 plays an important role in neuronal injury of epileptic rats by forming GluK2-PSD95-nNOS signaling module in a cytoplasmic calcium-dependent way, suggesting a potential therapeutic target site for epilepsy. | 29193067 |
| 2018-04-28 10:24:00 | In the CA1 hippocampal pyramidal cell, GluK2 traffics to the neuronal surface and synapse efficiently and the auxiliary subunits Neto1 and Neto2 caused no further enhancement of these two trafficking processes. GluK2 caused a more than 10-fold increase in synaptic transmission. It is the amino-terminal domains of GluK1 and GluK2 that control their strikingly different trafficking properties. | 28100490 |
| Type | IDs |
|---|---|
| Synonymous | GluK2, GluR6 |
| Gene |
UniProtKB-ID:
GRIK2_RAT
UniprotKB:
P42260
UniParc:
UPI000012B618
EMBL:
Z11715,
Z11548
Ensembl:
ENSRNOG00000000368
KO:
rno:54257
|
| Nucleutide sequences |
EMBL-CDS:
CAA77778.1,
CAA77647.1
Ensembl_TRS:
ENSRNOT00000076234
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000068172
RefSeq:
NP_062182.1
|
| Others |
UniRef100:
UniRef100_P42260
UniRef90:
UniRef90_P42260
UniRef50:
UniRef50_P42260
UniGene:
Rn.87696
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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