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54239 Chrnb2

54239

Chrnb2

cholinergic receptor nicotinic beta 2 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cholinergic receptor nicotinic beta 2 subunit

研究结论

Date Results Publications
2018-06-16 12:19:00 Study shows that alpha6beta2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty 28666811
2018-02-03 10:44:00 the mechanism of interaction between [Upsilon4E]GID and the agonist binding pockets of the alpha4beta2 and the halpha7 receptors, and to estimate their relative binding affinities, was investigated. 27721068
2017-02-25 10:07:00 findings indicate that alterations in expression of the alpha4beta2 subtype of nAChR may be involved in the molecular mechanism(s) underlying the cognitive deficit associated with vascular dementia 26858154
2015-06-27 10:16:00 Data show that although two cholinergic receptor nicotinic beta subunit 2 (beta2 subunit) mutations, F119Q and T59K, strongly enhanced the affinity of alpha-Conotoxin LvIA (LvIA), the beta2 mutation V111I substantially reduced the binding of LvIA. 25713061
2014-06-07 10:26:00 Data indicate that the affinity of alpha-CTxLvIA selectively blocks alpha3beta2 vs. alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. 24398291

名称对应

Type IDs
Gene
UniProtKB-ID: ACHB2_RAT
UniprotKB: P12390
UniParc: UPI000012526F
EMBL: AY574258, L31622
Ensembl: ENSRNOG00000020778
KO: rno:54239
Nucleutide sequences
EMBL-CDS: AAC78724.1, AAS90354.1
Ensembl_TRS: ENSRNOT00000028200
Protein sequencees
Ensembl_PRO: ENSRNOP00000028200
RefSeq: NP_062170.1
Others
UniRef100: UniRef100_P12390
UniRef90: UniRef90_Q9ERK7
UniRef50: UniRef50_Q9ERK7
UniGene: Rn.53978

全选

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研究热度

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