| Type | Description |
|---|---|
| Definition | guanylate cyclase 1, soluble, beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:46:00 | GUCY1B3 was upregulated in neonatal rat ventricular myocytes in response to ischemia and reperfusion (IR) injury, and restored IR-induced cell death and apoptosis. Other results suggest that GUCY1B3 has an antiapoptotic effect and this effect is mediated by the activation of and Akt. | 30485489 |
| 2019-03-16 12:15:00 | data have provided some evidence for an alteration in the expression of alpha1 and beta1 oluble guanylyl cyclase alternative splicing forms which may contribute to the loss of sGC functions in breast cancer | 30597209 |
| 2018-09-15 11:00:00 | Study shows notch signaling provides a constitutive drive on expression of the major nitric oxide receptor GUCY1A3 and GUCY1B3 in arteries from mice. | 28465505 |
| 2016-05-07 10:27:00 | Apo-sGC mice expressing haem-free sGC are viable and develop hypertension. The haemodynamic effects of NO are abolished, but those of the sGC activator cinaciguat are enhanced. | 26442659 |
| 2016-04-09 10:08:00 | NO-GC has a role in growth and plasticity of hindlimb and retinal vasculature after ischemic/hypoxic insult | 25795218 |
| Type | IDs |
|---|---|
| Synonymous | GC-S-beta-1, GCbeta1, Gucy1b3 |
| Gene |
UniProtKB-ID:
GCYB1_MOUSE,
Q80YP4_MOUSE,
Q3UTI4_MOUSE
UniprotKB:
O54865,
Q80YP4,
Q3UTI4
UniParc:
UPI0000028103,
UPI000018CE48,
UPI00005ABEEE
EMBL:
BC050945,
AF020339,
AK139406,
AF297083,
AC131757,
BC056995,
AC121563
Ensembl:
ENSMUSG00000028005
KO:
mmu:54195
|
| Nucleutide sequences |
EMBL-CDS:
AAB94876.1,
AAG17447.1,
AAH50945.1,
AAH56995.1,
BAE23996.1
Ensembl_TRS:
ENSMUST00000029635,
ENSMUST00000193597
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029635,
ENSMUSP00000142119
RefSeq:
NP_001155268.1,
NP_059497.1
|
| Others |
UniRef100:
UniRef100_Q80YP4,
UniRef100_O54865
UniRef90:
UniRef90_O54865,
UniRef90_Q4ZHR9
UniRef50:
UniRef50_Q02153
UniGene:
Mm.9445
CCDS:
CCDS38460.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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