| Type | Description |
|---|---|
| Definition | rabaptin, RAB GTPase binding effector protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 11:16:00 | Restoring C9ORF72 levels or augmenting its function with constitutively active RAB5 or chemical modulators of RAB5 effectors rescued patient neuron survival and ameliorated neurodegenerative processes in both gain- and loss-of-function C9ORF72 mouse models | 29400714 |
| 2015-12-12 10:48:00 | novel protein complex composed of Rabep1, GGA1 and Arl3 is responsible for the sorting and targeting of the polycystin 1 andpolycystin 2 to the cilium. | 25405894 |
| 2015-10-03 10:21:00 | The intracellular localization of Rabaptin-5gamma indicates that it is not involved in Rab5-driven events--rather, it functions in other membrane transport steps; role of alternative splicing in determination of functional activities of Rab effector molecules | 25385014 |
| 2014-06-07 11:04:00 | our results assign Rab5 a key role in mediating mast cell secretory granule fusion during biogenesis | 24696234 |
| 2013-06-01 12:02:00 | Rabex-5 regulates neurite morphogenesis of hippocampal neurons by activating at least two downstream targets, Rab5, which is localized in both axons and dendrites, and Rab17, which is localized in dendrites alone | 23430262 |
| Type | IDs |
|---|---|
| Synonymous | Rab5ep, rabaptin-5, rabaptin-5alpha |
| Gene |
UniProtKB-ID:
RABE1_MOUSE,
J3QJV7_MOUSE
UniprotKB:
O35551,
J3QJV7
UniParc:
UPI000019420D,
UPI0000434878,
UPI0000195458,
UPI0000193373,
UPI00001D9550,
UPI0000D8B5FF,
UPI0000ECF109
EMBL:
AL596136,
CR936845,
AF248489,
BC003921,
AK019413,
BC129853,
AB001750,
D86066,
CR933735,
CH466596,
AF248490,
BC129854,
BC060166
Ensembl:
ENSMUSG00000020817
KO:
mmu:54189
|
| Nucleutide sequences |
EMBL-CDS:
BAA21783.1,
AAH03921.1,
AAI29855.1,
AAG44544.1,
AAI29854.1,
BAB31710.3,
BAA23818.1,
EDL12625.1,
AAF78238.1,
AAH60166.1
Ensembl_TRS:
ENSMUST00000178245,
ENSMUST00000081362,
ENSMUST00000076270,
ENSMUST00000100928,
ENSMUST00000108533,
ENSMUST00000177731
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000075619,
ENSMUSP00000098488,
ENSMUSP00000080102,
ENSMUSP00000104173,
ENSMUSP00000137267,
ENSMUSP00000136069
RefSeq:
NP_001278070.1,
NP_001278071.1,
NP_001278072.1,
NP_062273.2,
XP_036012747.1,
XP_006533813.1
|
| Others |
UniRef100:
UniRef100_O35551
UniRef90:
UniRef90_Q15276
UniRef50:
UniRef50_Q15276
UniGene:
Mm.7087
CCDS:
CCDS78984.1,
CCDS24968.1,
CCDS70232.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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