| Type | Description |
|---|---|
| Definition | inducible T cell co-stimulator |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:18:00 | Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity. | 32160524 |
| 2020-05-16 10:14:00 | IL-6R cis-signaling is absolutely required for appropriate ICOS expression in Tfh cells. | 31413107 |
| 2020-05-02 10:51:00 | ICOS Knockout and ICOS mutated mice had similar severe defects in parasite-specific IgG production and parasite control compared to WT mice and observed expanded effector T cell populations and a loss of Treg frequency in the brains. | 31978191 |
| 2020-01-11 10:54:00 | these results suggest that IL-10 and ICOS differentially regulate T cell responses in the brain during chronic T. gondii infection. | 30718297 |
| 2019-10-26 10:37:00 | The results identify a novel role for ICOS costimulation in imprinting the functional stability of Foxp3 that is required for the retention of full Treg cell function in the periphery. | 30642977 |
| Type | IDs |
|---|---|
| Synonymous | AILIM, CCLP, CRP-1, H4, Ly115 |
| Gene |
UniProtKB-ID:
ICOS_MOUSE,
Q3V3X2_MOUSE,
Q5SUZ7_MOUSE
UniprotKB:
Q9WVS0,
Q3V3X2,
Q5SUZ7
UniParc:
UPI0000028B78,
UPI00005AB5B8
EMBL:
AJ250559,
AB023132,
AF327185,
AF327184,
AK030827,
AF257230,
BC034852,
GQ420691,
AF216748
Ensembl:
ENSMUSG00000026009
KO:
mmu:54167
|
| Nucleutide sequences |
EMBL-CDS:
AAF70099.1,
BAA82126.1,
CAB71153.1,
AAG48732.1,
AAH34852.1,
AAF45150.1,
BAE20458.1,
ACX50463.1
Ensembl_TRS:
ENSMUST00000102827
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099891
RefSeq:
NP_059508.2,
XP_006496203.1,
XP_006496202.1,
XP_006496201.1
|
| Others |
UniRef100:
UniRef100_Q3V3X2,
UniRef100_Q9WVS0
UniRef90:
UniRef90_Q9WVS0
UniRef50:
UniRef50_Q9R1T7
UniGene:
Mm.42044
CCDS:
CCDS14994.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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