| Type | Description |
|---|---|
| Definition | cancer/testis antigen family 45 member A1 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 11:17:00 | Following CT45A1 silencing, the expressions of Bcl2, survivin, MMP2, MMP9, pERK1/2 and pCREB were downregulated and the expression of Bax was upregulated. | 28901509 |
| 2016-05-21 11:12:00 | These data verify CT45 expression and promoter hypomethylation as possible prognostic biomarkers, and suggest CT45 as an immunological or therapeutic target in Epithelial ovarian cancer | 26098711 |
| 2015-02-14 13:40:00 | CT45A1 functions as a novel proto-oncogene to trigger oncogenesis and metastasis. | 24901056 |
| 2010-05-31 11:24:00 | Hodgkin lymphoma has the highest CT45 expression among all malignancies tested, in diffuse large B-cell lymphomas it is similar to that seen in epithelial cancers, and not present in low-grade non-Hodgkin B-cell lymphomas. | 20133697 |
| 2010-01-21 00:00:00 | Over-expression of CT45 is associated with cancer. | 19296537 |
| Type | IDs |
|---|---|
| Synonymous | CT45, CT45-1, CT45.1 |
| Gene |
UniProtKB-ID:
CT451_HUMAN
UniprotKB:
Q5HYN5
UniParc:
UPI000013EAEA
EMBL:
AC240442,
BC140913,
AY743709
Ensembl:
ENSG00000268940
KO:
hsa:541466
|
| Nucleutide sequences |
EMBL-CDS:
AAW66464.1,
AAI40914.1
Ensembl_TRS:
ENST00000594117,
ENST00000594565
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000472303,
ENSP00000470185
RefSeq:
NP_001017417.1,
XP_011529654.1,
XP_005278198.1
|
| Others |
UniRef100:
UniRef100_Q5HYN5
UniRef90:
UniRef90_Q5HYN5
UniRef50:
UniRef50_Q5HYN5
UniGene:
Hs.460937
CCDS:
CCDS48174.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28901509 |
Mol Med Rep Feng Tang , Shengjun Tang , Xiaolong Guo , Chao Yang , Ke Jia |
2017-11-01 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26098711 |
Epigenetics Wa Zhang , Carter J Barger , Petra A Link , Paulette Mhawech-Fauceglia , Austin Miller , Stacey N Akers , Kunle Odunsi , Adam R Karpf |
2015-01-01 | - |
| 24901056 |
CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis. Cell Death Dis B Shang , A Gao , Y Pan , G Zhang , J Tu , Y Zhou , P Yang , Z Cao , Q Wei , Y Ding , J Zhang , Y Zhao , Q Zhou |
2014-01-01 |
CT45A1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20133697 |
Expression of cancer testis antigen CT45 in classical Hodgkin lymphoma and other B-cell lymphomas. Proc. Natl. Acad. Sci. U.S.A. Yao-Tseng Chen , Amy Chadburn , Peishan Lee , Melinda Hsu , Erika Ritter , April Chiu , Sacha Gnjatic , Michael Pfreundschuh , Daniel M Knowles , Lloyd J Old |
2010-02-16 |
CT45A1
|
| 19296537 |
Cancer/testis antigen CT45: analysis of mRNA and protein expression in human cancer. Int. J. Cancer Yao-Tseng Chen , Melinda Hsu , Peishan Lee , Sandra J Shin , Paulette Mhawech-Fauceglia , Kunle Odunsi , Nasser K Altorki , Chao-Jun Song , Bo-Quan Jin , Andrew J Simpson , Lloyd J Old |
2009-06-15 |
CT45A1
|
| 15905330 |
Identification of cancer/testis-antigen genes by massively parallel signature sequencing. Proc. Natl. Acad. Sci. U.S.A. Yao-Tseng Chen , Matthew J Scanlan , Charis A Venditti , Ramon Chua , Gregory Theiler , Brian J Stevenson , Christian Iseli , Ali O Gure , Tom Vasicek , Robert L Strausberg , C Victor Jongeneel , Lloyd J Old , Andrew J G Simpson |
2005-05-31 |
CT45B1P,
CT45A7,
CT45A10,
CT45A9,
CT45A8,
CT62,
LINC01193,
CT45A3,
CT45A5,
CT45A6,
CT45A1,
LINC01192,
CT45A2
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
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|---|---|---|
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