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54137 Acrbp

54137

Acrbp

proacrosin binding protein

protein-coding

Mus musculus

基因描述

Type Description
Definition proacrosin binding protein

研究结论

Date Results Publications
2019-08-31 12:19:00 Male subfertility of ACRBP-deficient mice may be attributed to incompleteness of the acrosome reaction rather than impairment in sperm migration from the uterus to the oviduct. 30606959
2019-01-26 11:13:00 Setd2 deficiency results in complete loss of H3K36me3 and significantly decreases expression of thousands of genes, including those encoding acrosin-binding protein 1 (Acrbp1) and protamines, required for spermatogenesis. 29716999
2017-12-16 12:25:00 ACRBP-null male mice showed a severely reduced fertility, because of malformation of the acrosome. 27303034
2013-11-16 12:03:00 Two forms of Acrbp mRNA-wild-type Acrbp-W and variant Acrbp-V5 mRNAs-were generated by alternative splicing of Acrbp in the mouse. 23426433
2012-09-29 10:41:00 Data suggest that the fertility defect in PCSK4 (proprotein convertase subtilisin/kexin type 4) knockout mice is due, in part, to altered processing/proteolysis of ACRBP as well as structural abnormalities in sperm heads and acrosomes. 22357636

名称对应

Type IDs
Synonymous OY-TES-1, sp32
Gene
UniProtKB-ID: ACRBP_MOUSE
UniprotKB: Q3V140
UniParc: UPI0000023486, UPI00000E6509
EMBL: BC011079, D17573, AK076691, AK132705, D17574
Ensembl: ENSMUSG00000072770
KO: mmu:54137
Nucleutide sequences
EMBL-CDS: BAA04498.1, AAH11079.1, BAA04499.1, BAC36445.1, BAE21313.1
Ensembl_TRS: ENSMUST00000112414, ENSMUST00000088294
Protein sequencees
Ensembl_PRO: ENSMUSP00000085632, ENSMUSP00000108033
RefSeq: NP_001120812.1, NP_058541.2
Others
UniRef100: UniRef100_Q3V140
UniRef90: UniRef90_Q3V140
UniRef50: UniRef50_Q3V140
UniGene: Mm.347910
CCDS: CCDS51910.1, CCDS20542.1

全选

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研究热度

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