| Type | Description |
|---|---|
| Definition | polymerase (DNA directed), mu |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 10:25:00 | The atomic structure of an NHEJ junction with a Pol x construct that mimics Pol mu in a reconstituted system explained the distinctive properties of Pol mu compared with TdT. The structure suggested a mechanism of base selection relying on Loop1 and taking instructions via the in trans templating base independently of the primer strand. | 31138645 |
| 2018-04-14 10:22:00 | Findings demonstrate that Polmu is necessary for proper retinal development, and support that the generation of DNA double-strand breaks and their repair via the non-homologous end-joining pathway are genuine processes involved in neural development. | 27172884 |
| 2017-08-19 10:28:00 | A role for PolMU in the prevention of sarcomagenesis on a murine P53-deficient background was identified. | 28460268 |
| 2016-04-30 10:25:00 | Pol mu and Pol lambda play a key role in conferring on NHEJ the flexibility required for accurate and efficient repair | 26240371 |
| 2015-12-19 10:14:00 | Polmu deficiency activates transcriptional networks that reduce constitutive apoptosis, leading to enhanced liver repair at old age. | 24691161 |
| Type | IDs |
|---|---|
| Synonymous | AI462166, B230309I03Rik, Tdt-N |
| Gene |
UniProtKB-ID:
DPOLM_MOUSE
UniprotKB:
Q9JIW4
UniParc:
UPI000002192C
EMBL:
AL627069,
AF176098,
AJ251804,
CH466574
Ensembl:
ENSMUSG00000020474
KO:
mmu:54125
|
| Nucleutide sequences |
EMBL-CDS:
AAF27552.1,
EDL40561.1,
CAB71154.1
Ensembl_TRS:
ENSMUST00000020767
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020767
RefSeq:
XP_006514821.1,
NP_059097.2,
XP_036012744.1,
XP_006514822.1,
XP_036012745.1,
XP_030102018.1
|
| Others |
UniRef100:
UniRef100_Q9JIW4
UniRef90:
UniRef90_Q9JIW4
UniRef50:
UniRef50_Q9JIW4
UniGene:
Mm.260194
CCDS:
CCDS24405.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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