| Type | Description |
|---|---|
| Definition | DNA polymerase epsilon 3, accessory subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 11:44:00 | We studied the expression profile of the 60 genes located at that genomic region. POLE3 and AKNA were the only two genes deregulated in resistant tumors harboring the 9q32-q33.1 gain | 29618620 |
| 2019-04-20 11:11:00 | iochemical analyses establish that POLE3-POLE4 is a histone chaperone that promotes tetrasome formation and DNA supercoiling in vitro. In cells, POLE3-POLE4 binds both newly synthesized and parental histones, and its depletion hinders helicase unwinding and chromatin PCNA unloading and compromises coordinated parental histone retention and new histone deposition | 30217558 |
| Type | IDs |
|---|---|
| Synonymous | CHARAC17, CHRAC17, CHRAC2, YBL1, p17 |
| Gene |
UniProtKB-ID:
DPOE3_HUMAN,
A0A024R829_HUMAN
UniprotKB:
Q9NRF9,
A0A024R829
UniParc:
UPI0000001BE2
EMBL:
AF226077,
AL137066,
BC004170,
CH471090,
AK074762,
AK074782,
DQ072116,
AY720898,
AK074629,
AF261689,
BC003166
Ensembl:
ENSG00000148229
KO:
hsa:54107
|
| Nucleutide sequences |
EMBL-CDS:
BAC11099.1,
AAF90133.1,
BAC11190.1,
AAF72417.1,
AAY57326.1,
AAH03166.1,
AAH04170.1,
AAU15052.1,
BAC11206.1,
EAW87382.1,
EAW87381.1
Gene_ORFName:
hCG_29189
Ensembl_TRS:
ENST00000374169,
ENST00000374171
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363286,
ENSP00000363284
RefSeq:
NP_001265184.1,
NP_059139.3
|
| Others |
UniRef100:
UniRef100_Q9NRF9
UniRef90:
UniRef90_Q9NRF9
UniRef50:
UniRef50_Q9NRF9
UniGene:
Hs.108112
CCDS:
CCDS6795.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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