| Type | Description |
|---|---|
| Definition | thrombospondin type laminin G domain and EAR repeats |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | Novel TSPEAR mutations in non-syndromic oligodontia. | 32112661 |
| 2018-09-29 10:38:00 | TSPEAR mutation is associated with tooth agenesis. | 30046887 |
| 2017-05-13 16:06:00 | using a luciferase-based reporter assay, we showed that TSPEAR knock-down is associated with decreased Notch signaling. In addition, NOTCH1 protein expression was reduced in patient scalp skin. Moreover, TSPEAR silencing in mouse hair follicle organ cultures was found to induce apoptosis in follicular epithelial cells, resulting in decreased hair bulb diameter | 27736875 |
| 2017-03-22 10:11:00 | TSPEAR expression is significantly downregulated in human masticatory mucosa during wound healing | 28005267 |
| 2012-12-22 11:43:00 | TSPEAR, cause disorders with auditory features: epilepsy, which can include auditory features in humans; audiogenic seizures in animals; and/or hearing impairments in humans and mice. | 22678063 |
| Type | IDs |
|---|---|
| Synonymous | C21orf29, DFNB98, ECTD14, TSP-EAR |
| Gene |
UniProtKB-ID:
TSEAR_HUMAN
UniprotKB:
Q8WU66
UniParc:
UPI000002B65A,
UPI0000137746
EMBL:
AJ487962,
BC021197
Ensembl:
ENSG00000175894
KO:
hsa:54084
|
| Nucleutide sequences |
EMBL-CDS:
CAD32309.1,
AAH21197.2
Ensembl_TRS:
ENST00000323084
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000321987
RefSeq:
NP_659428.2,
NP_001258966.1
|
| Others |
UniRef100:
UniRef100_Q8WU66
UniRef90:
UniRef90_Q8WU66
UniRef50:
UniRef50_Q8WU66
UniGene:
Hs.660703
CCDS:
CCDS13712.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32112661 |
Novel TSPEAR mutations in non-syndromic oligodontia. Oral Dis Ji-Soo Song , Miah Bae , Jung-Wook Kim |
2020-05-01 | - |
| 31391242 |
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. J Cell Sci Marcel Nowak , Benjamin Suenkel , Pablo Porras , Rebekka Migotti , Franziska Schmidt , Melanie Kny , Xiaoxi Zhu , Erich E Wanker , Gunnar Dittmar , Jens Fielitz , Thomas Sommer |
2019-09-06 | - |
| 30046887 |
Hum. Genet. Renqian Du , Nuriye Dinckan , Xiaofei Song , Zeynep Coban-Akdemir , Shalini N Jhangiani , Yeliz Guven , Oya Aktoren , Hulya Kayserili , Lauren E Petty , Donna M Muzny , Jennifer E Below , Eric Boerwinkle , Nan Wu , Richard A Gibbs , Jennifer E Posey , James R Lupski , Ariadne Letra , Z Oya Uyguner |
2018-09-01 | - |
| 28005267 |
Human gingiva transcriptome during wound healing. J. Clin. Periodontol. Yun Wang , Dimitris N Tatakis |
2017-04-01 | - |
| 27736875 |
PLoS Genet. Alon Peled , Ofer Sarig , Liat Samuelov , Marta Bertolini , Limor Ziv , Daphna Weissglas-Volkov , Marina Eskin-Schwartz , Christopher A Adase , Natalia Malchin , Ron Bochner , Gilad Fainberg , Ilan Goldberg , Koji Sugawara , Avital Baniel , Daisuke Tsuruta , Chen Luxenburg , Noam Adir , Olivier Duverger , Maria Morasso , Stavit Shalev , Richard L Gallo , Noam Shomron , Ralf Paus , Eli Sprecher |
2016-10-01 | - |
| 22678063 |
Hum. Mol. Genet. Sedigheh Delmaghani , Asadollah Aghaie , Nicolas Michalski , Crystel Bonnet , Dominique Weil , Christine Petit |
2012-09-01 |
Tspear,
Tspear,
TSPEAR,
TSPEAR
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20494980 |
Nucleic Acids Res. Hans-Jörg Warnatz , Robert Querfurth , Anna Guerasimova , Xi Cheng , Stefan A Haas , Andrew L Hufton , Thomas Manke , Dominique Vanhecke , Wilfried Nietfeld , Martin Vingron , Michal Janitz , Hans Lehrach , Marie-Laure Yaspo |
2010-10-01 |
RWDD2B,
BRWD1-IT2,
B3GALT5,
FTCD,
ADAMTS5,
B3GALT5-AS1,
LINC00479,
CLDN14,
LINC00315,
BACE2,
C2CD2,
KRTAP13-4,
LINC00319,
GRIK1,
AIRE,
KRTAP11-1,
KRTAP13-2,
KRTAP19-5,
KCNE1,
KCNJ6,
COL18A1-AS1,
MX1,
MX2,
PCP4,
UBASH3A,
LRRC3DN,
TSPEAR,
H2BFS,
C21orf62,
MRAP,
SLC19A1,
TFF1,
CBR3,
PAXBP1
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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