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54069 MIS18A

54069

MIS18A

MIS18 kinetochore protein A

protein-coding

Homo sapiens

基因描述

Type Description
Definition MIS18 kinetochore protein A

研究结论

Date Results Publications
2020-01-04 10:09:00 Data show that the MIS18 kinetochore protein A (Mis18alpha) N-terminal region modulates Holliday junction recognition protein (HJURP) binding. 31492860
2018-02-10 11:31:00 The authors demonstrate that CDK1 controls Mis18 complex recruitment to centromeres by regulating oligomerization of M18BP1 through the Mis18alpha:Mis18beta scaffold. 28059702
2017-09-23 10:11:00 the Mis18 complex contains dual CENP-C recognition motifs that are combinatorially required to generate robust centromeric localization that leads to CENP-A deposition 27239045
2017-07-22 10:25:00 Mis18alpha is important for epidermal cell proliferation and stratification, because it is required for the deposition of CENP-A at the centromeric nucleosomes. 27670610
2016-07-30 10:39:00 Stable binding of Mis18alpha-Mis18beta heterotetramer to centromeres in telophase licenses them for CENP-A deposition. 26942680

名称对应

Type IDs
Synonymous B28, C21orf45, C21orf46, FASP1, MIS18alpha, hMis18alpha
Gene
UniProtKB-ID: MS18A_HUMAN
UniprotKB: Q9NYP9
UniParc: UPI0000000C0D
EMBL: AK312073, BC042917, AF387845, AF231921, CH471079, AK075281
Ensembl: ENSG00000159055
KO: hsa:54069
Nucleutide sequences
EMBL-CDS: BAC11517.1, AAK70498.1, EAX09881.1, BAG35009.1, AAF72945.1, AAH42917.1
Ensembl_TRS: ENST00000290130
Protein sequencees
Ensembl_PRO: ENSP00000290130
RefSeq: XP_016883890.1, NP_061817.1, XP_016883889.1, XP_016883891.1
Others
UniRef100: UniRef100_Q9NYP9
UniRef90: UniRef90_Q9NYP9
UniRef50: UniRef50_Q9NYP9
UniGene: Hs.190518
CCDS: CCDS13611.1

全选

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