| Type | Description |
|---|---|
| Definition | pancreatic lipase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:48:00 | Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation. | 31917686 |
| 2020-02-29 10:32:00 | Our data indicate that protease-sensitive PNLIP variants are novel genetic risk factors for the development of CP. | 30789418 |
| 2017-05-20 14:00:00 | Serum lipase subtype analysis cannot replace the standard lipase measurement for the diagnosis of acute pancreatitis, but the test demonstrated adequate sensitivity for use in triage or as an add-on test for serum lipase elevation. | 27243230 |
| 2015-08-29 11:31:00 | Presence of methionine at position 221 in the PNLIP protein sequence causes protein misfolding and aggregation. | 25862608 |
| 2015-02-14 12:38:00 | All these findings support the use of YLLIP2 in enzyme replacement therapy for the treatment of pancreatic exocrine insufficiency, a pathological situation in which an acidification of intestinal contents occurs. | 24650780 |
| Type | IDs |
|---|---|
| Synonymous | PL, PNLIPD, PTL |
| Gene |
UniProtKB-ID:
LIPP_HUMAN
UniprotKB:
P16233
UniParc:
UPI000004F1A0
EMBL:
L11242,
L24523,
L24526,
L24502,
AK313941,
L24527,
L24529,
L24522,
AL731653,
L24525,
J05125,
BC014309,
CH471066,
L24528,
M93285
Ensembl:
ENSG00000175535
KO:
hsa:5406
|
| Nucleutide sequences |
EMBL-CDS:
AAA99053.1,
BAG36659.1,
AAA36740.1,
AAA60129.1,
AAH14309.1,
EAW49451.1
Ensembl_TRS:
ENST00000369221
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358223
RefSeq:
NP_000927.1
|
| Others |
UniRef100:
UniRef100_P16233
UniRef90:
UniRef90_P16233
UniRef50:
UniRef50_P16233
UniGene:
Hs.501135
CCDS:
CCDS7594.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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