| Type | Description |
|---|---|
| Definition | diaphanous related formin 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 10:18:00 | individual and combined, CRISPR/Cas9-mediated disruption of genes encoding mDia1 and -3 formins in B16-F1 mouse melanoma cells revealed enhanced frequency of cells displaying multiple fronts, again accompanied by defects in cell polarization and migration | 30808751 |
| 2019-04-27 11:56:00 | Loss of mDia1/3 impaired these F-actin architectures, induced ectopic noncontractile espin1-containing F-actin bundles, and disrupted Sertoli cell-germ cell interaction, resulting in impaired spermatogenesis. | 30256801 |
| 2017-11-25 14:08:00 | mDia induces circumferential actin filaments around the edge of the synaptic cleft, which contract the presynaptic terminals in a ROCK-dependent manner. | 27880913 |
| 2016-09-07 12:19:00 | These results imply that RhoD activated by FGF signaling forms cytoneme-like protrusions through activation of mDia3C, which induces actin filament formation | 23034183 |
| 2014-03-08 12:28:00 | study examined how mDia functions in axon guidance in vivo and in vitro; findings show mDia plays multiple roles in the proper formation of the neural network | 23890216 |
| Type | IDs |
|---|---|
| Synonymous | Dia3, Diap2, Drf2, E430022I22Rik |
| Gene |
UniProtKB-ID:
DIAP2_MOUSE,
Q6W4W7_MOUSE,
K4PWM5_MOUSE
UniprotKB:
O70566,
Q6W4W7,
K4PWM5
UniParc:
UPI000022FFAE,
UPI000023B7F5,
UPI00028A4991
EMBL:
AL954869,
AB713187,
AL683857,
AK088648,
BX813314,
AL807775,
Y15910,
AY312280,
AL732443,
AL683856
Ensembl:
ENSMUSG00000034480
KO:
mmu:54004
|
| Nucleutide sequences |
EMBL-CDS:
BAC40476.1,
CAA75871.1,
AAQ82539.1,
BAM62938.1
Ensembl_TRS:
ENSMUST00000113320,
ENSMUST00000037854
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108946,
ENSMUSP00000039334
RefSeq:
XP_030107245.1,
XP_006528644.1,
XP_036017911.1,
NP_766081.1,
XP_006528645.1
|
| Others |
UniRef100:
UniRef100_K4PWM5,
UniRef100_O70566,
UniRef100_Q6W4W7
UniRef90:
UniRef90_O70566
UniRef50:
UniRef50_O60879
UniGene:
Mm.10763
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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