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54003 Nell2

54003

Nell2

NEL-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition NEL-like 2

研究结论

Date Results Publications
2020-06-27 11:56:00 Male mice in which Nell2 had been knocked out were infertile. 32499443
2020-01-04 11:00:00 Nell2 acts as a domain-specific positional label in the dorsal lateral geniculate nucleus that discriminates contralateral and ipsilateral retinal ganglion cell axons, and it plays essential roles in the establishment of the eye-specific retinogeniculate projection 30745429
2017-09-23 13:42:00 Cytosolic NELL2 specifically interacts with beta isotypes and inhibits duanyu1531 beta1 through direct binding to the N-terminal pseudosubstrate domain of duanyu1531 beta1. 25450684
2016-01-16 10:07:00 These findings identify NELL2 as an axon guidance cue and establish Robo3 as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 repulsion, inhibits Slit repulsion, and facilitates Netrin attraction to achieve a common guidance purpose. 26586761
2014-11-08 13:39:00 NELL2 plays an important role in the regulation of neuronal differentiation via control of N-cadherin expression and cell aggregation. 24465772

名称对应

Type IDs
Synonymous A330108N19Rik, R75516, mel91
Gene
UniProtKB-ID: NELL2_MOUSE
UniprotKB: Q61220
UniParc: UPI0000021EFA
EMBL: U59230, AC164402, AC109198, BC051968, AC163991
Ensembl: ENSMUSG00000022454
KO: mmu:54003
Nucleutide sequences
EMBL-CDS: AAH51968.1, AAB02924.1
Ensembl_TRS: ENSMUST00000075275, ENSMUST00000166170
Protein sequencees
Ensembl_PRO: ENSMUSP00000131665, ENSMUSP00000074751
RefSeq: NP_001276582.1, XP_006521227.1, NP_001343880.1, XP_036015412.1, NP_001343879.1, XP_006521226.1
Others
UniRef100: UniRef100_Q61220
UniRef90: UniRef90_Q62918
UniRef50: UniRef50_Q62918
UniGene: Mm.3959
CCDS: CCDS27775.1

全选

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研究热度

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