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53947 A4GALT

53947

A4GALT

alpha 1,4-galactosyltransferase (P blood group)

protein-coding

Homo sapiens

基因描述

Type Description
Definition alpha 1,4-galactosyltransferase (P blood group)

研究结论

Date Results Publications
2021-04-13 10:12:00 The interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection. 32507026
2020-09-12 16:06:00 Two Thai Burmese descendants with A4GALT*01N.21, p phenotype, and anti-PP1Pk. 32667820
2019-08-17 10:14:00 After serological and molecular biology tests on the patient and her family members, we confirmed that the patient and her sister possessed p phenotype, and the habitual abortion that occurred in the patient was caused by the anti-PP1Pk antibody. The p phenotype is a rare phenotype in P1Pk blood system, individuals with p phenotype lack all of the antigens of the P1Pk blood system and possess anti-PP1Pk antibody in their 31374005
2019-05-18 11:41:00 These data indicate that RUNX1 regulates A4GALT and thereby the expression of clinically important glycosphingolipids implicated in blood group incompatibility and host-pathogen interactions. 29438961
2018-11-17 11:24:00 The differential binding of transcription factor early growth response 1 to the SNP rs5751348 genomic region with the different genotypes in the A4GALT gene leads to differential activation of P(1) -A4GALT and P(2) -A4GALT expression. 29399809

名称对应

Type IDs
Synonymous A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK
Gene
UniProtKB-ID: A4GAT_HUMAN, A0A0S2Z5J1_HUMAN
UniprotKB: Q9NPC4, A0A0S2Z5J1
UniParc: UPI000003FF92
EMBL: BC017068, AB037883, CH471138, AK312927, AY941797, AJ245581, Z82176, KU178649, AB041418
Ensembl: ENSG00000128274
KO: hsa:53947
Nucleutide sequences
EMBL-CDS: CAB93532.1, AAX20109.1, AAH17068.1, BAG35771.1, BAA95915.1, BAA94503.1, EAW73274.1, ALQ34107.1
Ensembl_TRS: ENST00000381278, ENST00000642412, ENST00000249005, ENST00000401850
Protein sequencees
Ensembl_PRO: ENSP00000370678, ENSP00000494127, ENSP00000249005, ENSP00000384794
RefSeq: XP_006724329.1, NP_059132.1, NP_001304967.1, XP_005261705.1, XP_016884320.1, XP_005261701.1, XP_005261703.1, XP_011528535.1, XP_005261704.1, XP_006724328.1
Others
UniRef100: UniRef100_Q9NPC4
UniRef90: UniRef90_Q9NPC4
UniRef50: UniRef50_Q9NPC4
UniGene: Hs.105956
CCDS: CCDS14041.1

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