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53918 PELO

53918

PELO

pelota mRNA surveillance and ribosome rescue factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition pelota mRNA surveillance and ribosome rescue factor

研究结论

Date Results Publications
2017-11-18 13:34:00 Induction of ribosome rescue factors PELO and HBS1L is required to support protein synthesis when ABCE1 levels fall in platelets, including for hemoglobin production during blood cell development. 27681415
2017-08-12 10:23:00 The data suggest that the decay of platelet mRNAs is slowed by the natural loss of the mRNA surveillance and ribosome rescue factor Pelota. 28213379
2017-05-13 17:03:00 Human Pelota compensated for Dom34 functions in quality control of nonstop mRNA in yeast. 27543824
2014-04-26 11:46:00 PELO is a novel regulator of HER-signalling. 23435426
2013-08-31 10:16:00 The non-stop decay mechanism exists in mammalian cells and involves Hbs1, Dom34, and the exosome-Ski complex. 23667253

名称对应

Type IDs
Synonymous CGI-17, PRO1770
Gene
UniProtKB-ID: PELO_HUMAN
UniprotKB: Q9BRX2
UniParc: UPI000013D9FE
EMBL: AF132951, BC007249, AF143952, AC026230, AY117399, BC005889, BC007650, BC022789, AF139828
Ensembl: ENSG00000152684
KO: hsa:53918
Nucleutide sequences
EMBL-CDS: AAH22789.1, AAM89414.1, AAD27726.1, AAH07650.1, AAH05889.1, AAG22575.1, AAG22574.1, AAH07249.1
Gene_ORFName: CGI-17
Ensembl_TRS: ENST00000274311
Protein sequencees
Ensembl_PRO: ENSP00000274311
RefSeq: NP_057030.3
Others
UniRef100: UniRef100_Q9BRX2
UniRef90: UniRef90_Q9BRX2
UniRef50: UniRef50_Q9BRX2
UniGene: Hs.644352
CCDS: CCDS3956.1

全选

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研究热度

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