| Type | Description |
|---|---|
| Definition | myosin IIIA |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 12:02:00 | Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss. | 29880844 |
| 2017-05-27 10:19:00 | MYO3A is more efficient than MYO3B at increasing formation and elongation of stable microvilli on the surface of cultured epithelial cells. | 27582493 |
| 2017-01-14 11:17:00 | The structures of Myo3 in complex with Espin1 not only elucidate the mechanism of the binding, but also reveal a Myo3-induced release of Espin1 auto-inhibition mechanism. | 26785147 |
| 2016-12-31 10:10:00 | Study reports an amino acid substitution in MYO3A motor-head domain disrupting its ATPase activity that can cause autosomal dominant progressive hereditary hearing loss. Also, these results uncovered a novel interaction between MYO3A and PCDH15 shedding new light on the function of myosin IIIA at stereocilia tips. | 26841241 |
| 2016-12-17 10:39:00 | A homozygous mutation, MYO3A:c.1841C>T (p.S614F), was identified to be responsible for non-syndromic congenital deafness in two members of a Kazakh family in China. | 27063751 |
| Type | IDs |
|---|---|
| Synonymous | DFNB30 |
| Gene |
UniProtKB-ID:
MYO3A_HUMAN
UniprotKB:
Q8NEV4
UniParc:
UPI000014140A,
UPI00001F9050
EMBL:
BC036079,
AL391812,
AY101367,
AL358612,
AF229172,
AL360217,
AL162503
Ensembl:
ENSG00000095777
KO:
hsa:53904
|
| Nucleutide sequences |
EMBL-CDS:
AAF70861.1,
AAM34500.1,
AAH36079.1
Ensembl_TRS:
ENST00000376302,
ENST00000642920
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365479,
ENSP00000495965
RefSeq:
XP_011517807.1,
XP_011517808.1,
XP_011517805.1,
XP_011517804.1,
XP_011517802.1,
NP_001355194.1,
XP_011517801.1,
XP_011517815.1,
NP_059129.3,
XP_011517806.1,
XP_011517810.1,
XP_011517800.1,
XP_011517814.1,
XP_011517813.1,
XP_011517812.1
|
| Others |
UniRef100:
UniRef100_Q8NEV4
UniRef90:
UniRef90_Q8NEV4
UniRef50:
UniRef50_Q8NEV4
UniGene:
Hs.662630
CCDS:
CCDS7148.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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