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53831 GPR84

53831

GPR84

G protein-coupled receptor 84

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor 84

研究结论

Date Results Publications
2020-11-28 13:16:00 20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Receptor? 33001759
2019-10-26 10:22:00 Has a strong stimulatory effect on the expression of cytokine and chemokine genes, particularly CSF3, and on the expression of GPR84, a pro-inflammatory fatty acid receptor. 29775920
2018-09-08 10:40:00 GPR84 modulates TNFalpha mRNA expression in the LPS tolerant monocytes. 28404994
2018-07-14 12:14:00 we show functional similarities but also some important differences between GPR84 and FFA2R in human phagocytes, thus providing some mechanistic insights into GPR84 regulation in blood neutrophils and cells recruited to an aseptic inflammatory site in vivo. 29477577
2018-07-14 11:10:00 Data suggest that cytokines TNFalpha and interleukin-1b markedly reduce GPR120/FFAR4 expression in adipocytes; in contrast, these cytokines induce expression of GPR84 and GPR41/FFAR3 in adipocytes. These studies were conducted in adipocytes cultured from subcutaneous adipose tissue. (GPR = G-protein coupled receptor; FFAR = free fatty acid receptor) 28835131

名称对应

Type IDs
Synonymous EX33, GPCR4
Gene
UniProtKB-ID: GPR84_HUMAN
UniprotKB: Q9NQS5
UniParc: UPI00000421DF
EMBL: BC020614, AB083586, FJ348261, AF237762, CH471054, AF282693
Ensembl: ENSG00000139572
KO: hsa:53831
Nucleutide sequences
EMBL-CDS: AAF91467.1, AAK01857.1, BAB89299.1, AAH20614.1, ACI96305.1, EAW96776.1
Ensembl_TRS: ENST00000551809, ENST00000267015
Protein sequencees
Ensembl_PRO: ENSP00000267015, ENSP00000450310
RefSeq: XP_011536797.1, NP_065103.1
Others
UniRef100: UniRef100_Q9NQS5
UniRef90: UniRef90_Q9NQS5
UniRef50: UniRef50_Q9NQS5
UniGene: Hs.306199
CCDS: CCDS8878.1

全选

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