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53637 S1PR5

53637

S1PR5

sphingosine-1-phosphate receptor 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition sphingosine-1-phosphate receptor 5

研究结论

Date Results Publications
2019-08-03 10:49:00 our findings establish that S1PR5 is of central importance for human NK-cell response to sphingosine-1-phosphate and suggest that it is required for their egress from the bone marrow and secondary lymphoid organs. 29248494
2017-12-23 12:56:00 Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD. 27868302
2017-12-02 11:43:00 Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1-S1P pathway specifically in the control of mitosis in HeLa cells. 28351953
2015-08-29 10:41:00 TGF-beta2 dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF by TGF-beta in mesangial cells. 25601519
2015-02-28 13:27:00 This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss. 23551178

名称对应

Type IDs
Synonymous EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Gene
UniProtKB-ID: S1PR5_HUMAN
UniprotKB: Q9H228
UniParc: UPI0000350808, UPI000003BC79
EMBL: AC011461, AY262689, AK074661, AF317676, BC034703, AF331840, BC067781, AB083602
Ensembl: ENSG00000180739
KO: hsa:53637
Nucleutide sequences
EMBL-CDS: BAC11119.1, AAH34703.1, AAP20653.1, AAG38113.1, AAH67781.1, BAB89315.1, AAL57041.1
Ensembl_TRS: ENST00000439028, ENST00000333430
Protein sequencees
Ensembl_PRO: ENSP00000328472, ENSP00000416915
RefSeq: NP_001159687.1, NP_110387.1
Others
UniRef100: UniRef100_Q9H228
UniRef90: UniRef90_Q9H228
UniRef50: UniRef50_Q9H228
UniGene: Hs.501561
CCDS: CCDS12240.1

全选

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