| Type | Description |
|---|---|
| Definition | porcupine O-acyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:12:00 | Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis. | 31585741 |
| 2018-10-27 11:38:00 | Porcn mosaicism results in reduced fertility. | 29066530 |
| 2018-08-04 10:37:00 | This study showed that postnatal ablation of Porcupine in the uterine luminal epithelium alone results in the decrease in endometrial gland number; mutant females are completely infertile. | 29036275 |
| 2017-09-09 12:29:00 | Data suggest that PORCN exhibits substrate specificity that includes a Wnt3a peptide fragment (residues 199-219, with disulfide bonds); recombinant PORCN containing a point mutation (R228C) associated with focal dermal hypoplasia exhibits impaired acylation activity toward Wnt3a peptide fragment. (PORCN = porcupine O-acyltransferase; Wnt3a = Wnt family member 3A) | 28655768 |
| 2017-06-03 11:45:00 | Porcupine-dependent Wnt signaling, unlike previously reported, is dispensable for postnatal gland formation but is required for post-pubertal gland maintenance as well as for stromal cell proliferation. | 27965056 |
| Type | IDs |
|---|---|
| Synonymous | 2410004O13Rik, AW045557, DXHXS7465e, Mg61, Mporc, Ppn, mMg61, porc |
| Gene |
UniProtKB-ID:
PORCN_MOUSE
UniprotKB:
Q9JJJ7
UniParc:
UPI00000290F2,
UPI00000E84AA,
UPI00000287EC,
UPI0000028864,
UPI000002887E
EMBL:
AL663032,
AK010405,
AB036747,
AB036749,
BC032284,
AB036746,
AB036748
Ensembl:
ENSMUSG00000031169
KO:
mmu:53627
|
| Nucleutide sequences |
EMBL-CDS:
BAA89468.1,
AAH32284.1,
BAB26914.1,
BAA89469.1,
BAA89470.1,
BAA89467.1
Ensembl_TRS:
ENSMUST00000082320,
ENSMUST00000077595,
ENSMUST00000089402,
ENSMUST00000089403
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080937,
ENSMUSP00000086824,
ENSMUSP00000076790,
ENSMUSP00000086825
RefSeq:
XP_006527707.1,
NP_076127.1,
XP_036017907.1,
XP_030107243.1,
NP_058609.1,
NP_665915.1,
NP_665914.1,
XP_036017909.1,
XP_036017908.1,
NP_001295403.1
|
| Others |
UniRef100:
UniRef100_Q9JJJ7
UniRef90:
UniRef90_Q9JJJ7
UniRef50:
UniRef50_Q9JJJ7
UniGene:
Mm.443425
CCDS:
CCDS29991.1,
CCDS29992.1,
CCDS29993.1,
CCDS29990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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