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53626 Insm1

53626

Insm1

insulinoma-associated 1

protein-coding

Mus musculus

基因描述

Type Description
Definition insulinoma-associated 1

研究结论

Date Results Publications
2020-08-01 11:10:00 HuD and miR-203a cooperatively regulate INSM1 expression. 31722792
2019-07-20 11:00:00 Forced Insm1 expression in embryonic mouse neocortex causes neural progenitor cell delamination. 29503187
2019-06-08 10:57:00 Insm1, which encodes a zinc finger protein that is transiently expressed in nascent outer hair cells (OHC), consolidates their fate by preventing trans-differentiation into inner hair cells (IHC); in the absence of INSM1, many hair cells that are born as OHCs switch fates to become mature IHCs 30305733
2019-02-09 12:21:00 We conclude that decreases in Insm1 interfere with beta-cell specification during the early postnatal period and impair glucose homeostasis during metabolic stress in adults. Insm1 levels are therefore a factor that can influence the development of diabetes. 30257979
2018-04-14 10:28:00 An INSM1/RCOR1/2 complex controls the balance of proliferation and differentiation during brain development. 28049845

名称对应

Type IDs
Synonymous IA-1
Gene
UniProtKB-ID: INSM1_MOUSE, Q05BD7_MOUSE
UniprotKB: Q63ZV0, Q05BD7
UniParc: UPI00004408F1
EMBL: BC082809, BC051240, AF044669
Ensembl: ENSMUSG00000068154
KO: mmu:53626
Nucleutide sequences
EMBL-CDS: AAD15718.1, AAH82809.1, AAH51240.1
Ensembl_TRS: ENSMUST00000089257
Protein sequencees
Ensembl_PRO: ENSMUSP00000092048
RefSeq: NP_058585.2
Others
UniRef100: UniRef100_Q63ZV0
UniRef90: UniRef90_Q63ZV0
UniRef50: UniRef50_Q63ZV0
UniGene: Mm.379070
CCDS: CCDS16830.1

全选

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研究热度

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