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53624 Cldn7

53624

Cldn7

claudin 7

protein-coding

Mus musculus

基因描述

Type Description
Definition claudin 7

研究结论

Date Results Publications
2020-11-21 13:28:00 Upregulation of Claudin-7 Expression by Angiotensin II in Colonic Epithelial Cells of Mice Fed with NaCl-Depleted Diets. 32093310
2020-01-11 12:14:00 This study demonstrates that CLDN7 plays an important role in salt balance in renal CD cells and modulating WNK4 and ENaC expression levels that are vital in controlling salt-sensitive hypertension. 31382627
2019-04-06 10:48:00 The knockout of Claudin-7 in vivo causes extensive inflammation, atypical hyperplasia, and adenoma in intestinal tissue as well as animal death in mice. Claudin-7 may act as a tumor suppressor gene in the development of colorectal cancer. 30774273
2018-05-26 10:05:00 Intestinal Cldn7 deletion initiated inflammation and hyperplasia in mice. 29488037
2017-09-09 12:11:00 These results identify EpCAM as a substrate of matriptase and link HAI-2, matriptase, EpCAM, and claudin-7 in a functionally important pathway that causes disease when it is dysregulated. 28094766

名称对应

Type IDs
Gene
UniProtKB-ID: CLD7_MOUSE
UniprotKB: Q9Z261
UniParc: UPI0000003E62
EMBL: AK145504, AK167250, BC050007, AK002924, BC008104, AL596185, AK087296, AF087825
Ensembl: ENSMUSG00000018569
KO: mmu:53624
Nucleutide sequences
EMBL-CDS: BAE26475.1, BAE39371.1, AAD09760.1, AAH08104.1, AAH50007.1, BAB22460.1, BAC39839.1
Ensembl_TRS: ENSMUST00000108597, ENSMUST00000018713
Protein sequencees
Ensembl_PRO: ENSMUSP00000104238, ENSMUSP00000018713
RefSeq: NP_001180548.1, NP_058583.1
Others
UniRef100: UniRef100_Q9Z261
UniRef90: UniRef90_O95471
UniRef50: UniRef50_O95471
UniGene: Mm.281896
CCDS: CCDS24925.1

全选

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