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53623 Gria3

53623

Gria3

glutamate receptor, ionotropic, AMPA3 (alpha 3)

protein-coding

Mus musculus

基因描述

Type Description
Definition glutamate receptor, ionotropic, AMPA3 (alpha 3)

研究结论

Date Results Publications
2018-06-23 11:39:00 The central distribution of AMPARs is absent in GluA3-knockout mice, and gold particles are evenly distributed along the postsynaptic density. GluA4 gold labeling was homogenously distributed along both synapse types. Thus, GluA3 and GluA4 subunits are distributed at auditory nerve synapses in a target-cell-dependent manner. 28397107
2018-05-19 10:12:00 The experiments reveal a novel type of plasticity at CA1 hippocampal synapses that is expressed by the activation of GluA3-containing AMPARs. 28762944
2018-03-10 10:23:00 Results suggest a role for GluA3 channel activity in the regulation of sleep behavior in both mice and humans. 29016847
2018-03-03 11:49:00 GluA3 is required for normal auditory signaling, normal ultrastructure of AN-BC synapses in the cochlear nucleus and normal experience-dependent changes in auditory processing after transient sound reduction. 28011083
2018-02-03 10:08:00 These experiments indicate that the presence of GluA3-containing AMPARs is critical for Abeta-mediated synaptic and cognitive deficits. 27708157

名称对应

Type IDs
Synonymous 2900064I19Rik, GluA3, GluR-C, GluR-K3, Glur-3, Glur3, Gluralpha3
Gene
UniProtKB-ID: GRIA3_MOUSE, Q0VGS8_MOUSE, Q3UY17_MOUSE, B0QZW1_MOUSE
UniprotKB: Q9Z2W9, Q0VGS8, Q3UY17, B0QZW1
UniParc: UPI00005ABB41, UPI0000DBE455, UPI000024FDCB, UPI0000020BF0
EMBL: CH466570, AF483495, BC129855, AK135043, AB079072, AL672232, AK220530, BC086678, AL672290, AB022342, AF483494
Ensembl: ENSMUSG00000001986
KO: mmu:53623
Nucleutide sequences
EMBL-CDS: BAE06153.1, AAI29856.1, AAL90768.1, AAL90769.1, BAD90527.1, EDL29035.1, BAA37124.1, AAH86678.1, BAE22396.1
Ensembl_TRS: ENSMUST00000076349, ENSMUST00000115103, ENSMUST00000165288
Protein sequencees
Ensembl_PRO: ENSMUSP00000075687, ENSMUSP00000131523, ENSMUSP00000110755
RefSeq: NP_001345290.2, NP_058582.4, XP_017174035.1, NP_001268858.2, NP_001277380.2, XP_017174034.1, XP_017174036.1
Others
UniRef100: UniRef100_Q0VGS8, UniRef100_Q9Z2W9, UniRef100_B0QZW1
UniRef90: UniRef90_P19492
UniRef50: UniRef50_P19492
UniGene: Mm.327681
CCDS: CCDS30097.1

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研究热度

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