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53618 Fut8

53618

Fut8

fucosyltransferase 8

protein-coding

Mus musculus

基因描述

Type Description
Definition fucosyltransferase 8

研究结论

Date Results Publications
2020-12-26 13:14:00 Structural basis of substrate recognition and catalysis by fucosyltransferase 8. 32220931
2020-10-24 14:07:00 Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice. 32141499
2019-11-09 12:29:00 Core fucosylation negatively regulates the states of neuroinflammation by modulating the sensitivity of microglia and astrocytes to inflammatory mediators. The disorders of Fut8(-/-) mice are caused not only by neurons but also by glial cell dysfunction. 30572004
2015-11-28 10:42:00 our study provides the first direct evidence for the involvement of Fut8 in liver regeneration. 25652335
2015-10-03 11:19:00 Loss of core fucosylation on AMPARs enhanced their heteromerization, which increase sensitivity for postsynaptic depolarization and persistently activate N-methyl-d-aspartate receptors as well as Ca(2+) influx and CaMKII and then impair LTP. 25979332

名称对应

Type IDs
Gene
UniProtKB-ID: FUT8_MOUSE, B2X2D7_MOUSE, B2X2D8_MOUSE
UniprotKB: Q9WTS2, B2X2D7, B2X2D8
UniParc: UPI0001740D53, UPI0000004092, UPI0000354393
EMBL: AK051811, AK048520, BC010666, EF591874, EF591875, AB025198, CH466526
Ensembl: ENSMUSG00000021065
KO: mmu:53618
Nucleutide sequences
EMBL-CDS: BAA76392.1, EDL36443.1, AAH10666.1, BAC33357.1, BAC34777.1, EDL36441.1, ABV44380.1, ABV44381.1
Ensembl_TRS: ENSMUST00000177595, ENSMUST00000171770, ENSMUST00000062804
Protein sequencees
Ensembl_PRO: ENSMUSP00000054530, ENSMUSP00000136327, ENSMUSP00000130845
RefSeq: XP_011242447.1, XP_011242446.1, NP_001239545.1, NP_001239544.1, NP_058589.2, NP_001239543.1
Others
UniRef100: UniRef100_B2X2D8, UniRef100_Q9WTS2
UniRef90: UniRef90_Q9WTS2, UniRef90_B2X2D8
UniRef50: UniRef50_Q9WTS2, UniRef50_A0A3B3SUV6
UniGene: Mm.35628, Mm.489686
CCDS: CCDS25999.1

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