| Type | Description |
|---|---|
| Definition | methyl-CpG binding domain protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:13:00 | Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated downregulation. | 32181805 |
| 2020-11-28 13:10:00 | Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial-mesenchymal plasticity and tumor metastasis. | 31666683 |
| 2020-05-23 11:59:00 | our results demonstrate that mCG-binding arginine fingers embedded into a conserved structural fold are essential structural features for MBD2/3s binding to methylated DNA among metazoans. | 30980593 |
| 2019-07-20 12:52:00 | the interplay of the Zalpha domain from ADAR1 and MBD3 may regulate the transition of the DNA conformation between B- and Z-DNA and thereby modulate chromatin accessibility, resulting in alterations in gene expression | 30304469 |
| 2018-02-24 10:23:00 | Study have demonstrated that MBD3/ NuRD inhibits formation of liver induced cancer stem cells (iCSCs). In addition, MBD3 suppression induces c-JUN, resulting in the induction of pluripotent genes in iCSCs. | 27894081 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MBD3_HUMAN
UniprotKB:
O95983
UniParc:
UPI000000DA71,
UPI000003166B
EMBL:
CH471139,
BC009372,
AC005943,
AK290882,
AF072247,
BC043619,
BC032443,
BC009438
Ensembl:
ENSG00000071655
KO:
hsa:53615
|
| Nucleutide sequences |
EMBL-CDS:
EAW69478.1,
EAW69481.1,
AAH09438.1,
EAW69477.1,
BAF83571.1,
AAH43619.1,
AAC72104.1,
AAH09372.1,
AAC68876.1,
AAH32443.1
Ensembl_TRS:
ENST00000434436,
ENST00000156825
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412302,
ENSP00000156825
RefSeq:
NP_001268383.1,
NP_001268382.1
|
| Others |
UniRef100:
UniRef100_O95983
UniRef90:
UniRef90_O95983
UniRef50:
UniRef50_O95983
UniGene:
Hs.178728,
Hs.595754
CCDS:
CCDS62481.1,
CCDS12072.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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