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53614 Reck

53614

Reck

reversion-inducing-cysteine-rich protein with kazal motifs

protein-coding

Mus musculus

基因描述

Type Description
Definition reversion-inducing-cysteine-rich protein with kazal motifs

研究结论

Date Results Publications
2020-10-03 12:58:00 Structure of the RECK CC domain, an evolutionary anomaly. 32541044
2020-02-22 12:34:00 Mouse embryos carrying Reck(P256A,W261A) have severe defects in forebrain angiogenesis, providing the strongest evidence to date that Reck promotes central nervous system angiogenesis by specifically stimulating Wnt7a and Wnt7b signaling. 31225798
2018-10-20 10:40:00 Reck was identified to be one of the target genes of miR-497-5p, and Reck could suppress the expression of matrix metalloproteinase-2 (Mmp2) and Mmp9, which could activate latent transforming growth factor-beta1 (TGF-beta1). 28098218
2017-09-30 12:14:00 experiments indicate that Reck and Gpr124 are part of the cell surface protein complex that transduces Wnt7a- and Wnt7b-specific signals in mammalian CNS Epithelial Cells to promote angiogenesis and regulate the BBB. 28803732
2016-10-22 10:03:00 These findings demonstrate the importance of appropriate cell-cell interactions and ECM maintenance for angiogenesis and the involvement of Reck as a critical regulator of these events. 26658478

名称对应

Type IDs
Synonymous St15, mRECK
Gene
UniProtKB-ID: RECK_MOUSE, A2RSP9_MOUSE
UniprotKB: Q9Z0J1, A2RSP9
UniParc: UPI0000F059CD, UPI000024DE34
EMBL: BC132197, AB006960, AL773539, BC138065, AL772204
Ensembl: ENSMUSG00000028476
KO: mmu:53614
Nucleutide sequences
EMBL-CDS: BAA34061.1, AAI38066.1, AAI32198.1
Ensembl_TRS: ENSMUST00000030198
Protein sequencees
Ensembl_PRO: ENSMUSP00000030198
RefSeq: XP_030109534.1, NP_057887.2
Others
UniRef100: UniRef100_Q9Z0J1, UniRef100_A2RSP9
UniRef90: UniRef90_Q9Z0J1
UniRef50: UniRef50_Q9Z0J1
UniGene: Mm.331573
CCDS: CCDS18116.1

全选

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