| Type | Description |
|---|---|
| Definition | phospholipid transfer protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:25:00 | The selected compounds were further confirmed to target PLTP both biochemically and biophysically and were shown to inhibit apoB secretion from hepatic cells with no apparent toxicity. | 31017809 |
| 2019-12-14 11:36:00 | AAT protects PLTP from proteolytic cleavage and both AAT and PLTP mediate degranulation, possibly via Hck tyrosine kinase inhibition. Deficiency of AAT could contribute to reduced lung PLTP activity and elevated neutrophil signaling associated with lung disease. | 30337619 |
| 2019-11-02 13:01:00 | Profurin can interact with intracellular PLTP and promote its ubiquitination and proteasomal degradation, resulting in less PLTP secretion from the hepatocytes. Furin does not cleave PLTP; instead, it forms a complex with PLTP, likely through its prodomain | 29680823 |
| 2019-06-29 11:59:00 | REVIEW: the major progress made in the PLTP research field and emphasis on its impact on lipoprotein metabolism and atherosclerosis, as well as its regulation | 29438986 |
| 2019-02-02 12:02:00 | PLTP promotes platelet aggregation and is involved in hyper-coagulation | 30419596 |
| Type | IDs |
|---|---|
| Synonymous | BPIFE, HDLCQ9 |
| Gene |
UniProtKB-ID:
PLTP_HUMAN
UniprotKB:
P55058
UniParc:
UPI0001880BA1,
UPI0000131C7C,
UPI000016A238,
UPI000002B151
EMBL:
CH471077,
AK299181,
BC019898,
AB076694,
BC005045,
AK293150,
AK289371,
AL008726,
AY509570,
BC019847,
L26232
Ensembl:
ENSG00000100979
KO:
hsa:5360
|
| Nucleutide sequences |
EMBL-CDS:
AAH05045.1,
BAB79630.1,
AAA36443.1,
CAC36020.1,
EAW75781.1,
EAW75783.1,
BAF82060.1,
AAH19847.1,
CAA15499.1,
AAR87775.1,
AAH19898.1,
EAW75785.1,
BAG61226.1,
BAG56696.1,
EAW75782.1,
EAW75787.1
Ensembl_TRS:
ENST00000420868,
ENST00000372431,
ENST00000477313,
ENST00000354050,
ENST00000372420
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361497,
ENSP00000411671,
ENSP00000417138,
ENSP00000335290,
ENSP00000361508
RefSeq:
NP_872617.1,
NP_006218.1,
NP_001229850.1,
NP_001229849.1
|
| Others |
UniRef100:
UniRef100_P55058
UniRef90:
UniRef90_P55058
UniRef50:
UniRef50_P55058
UniGene:
Hs.439312
CCDS:
CCDS56196.1,
CCDS13387.1,
CCDS13386.1,
CCDS56197.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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