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53560 cic

53560

cic

capicua

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition capicua

研究结论

Date Results Publications
2020-12-05 13:03:00 Activation-induced substrate engagement in ERK signaling. 31913744
2020-10-24 14:07:00 Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. 32142631
2018-08-18 10:50:00 Cic regulated spatially restricted expression of Toll/IL-1 signaling targets in Drosophila embryogenesis. 29432195
2018-01-27 11:42:00 We have thus uncovered a previously unknown mechanism of down-regulation of Cic activity by Mnb and Wap, which operates independently from the ERK-mediated control of Cic. Therefore, Cic functions as an integrator of upstream signals that are essential for tissue patterning and organ growth 27601662
2017-09-30 11:50:00 Analysis of CSN1b mutant phenotypes revealed a requirement for the COP9 signalosome to prevent ectopic expression of Epidermal growth factor receptor (EGFR) target genes. It does so by protecting Capicua, a transcriptional repressor of EGFR target genes, from EGFR pathway-dependent ubiquitylation. 28619822

名称对应

Type IDs
Synonymous CG43122, CG5060, CG5067, CIC, Cic, Dmel\CG43122, Dmel_CG5060, Dmel_CG5067, E(Dl)D49, cics, fet
Gene
UniProtKB-ID: CIC_DROME, A0A0B4KGD7_DROME, A0A0B4K778_DROME, A0A0B4K6D6_DROME, A0A0B4K698_DROME
UniprotKB: Q9U1H0, A0A0B4KGD7, A0A0B4K778, A0A0B4K6D6, A0A0B4K698
UniParc: UPI00000075D4, UPI000237F678, UPI000237F676, UPI0002ADBD4A, UPI0002ADBCE7, UPI00015D9AE5
EMBL: AE014297, AJ252268, BT024235, BT044183
EnsemblGenome: FBgn0262582
KO: dme:Dmel_CG43122
Nucleutide sequences
EMBL-CDS: AAF55751.3, ABW08708.1, ABC86297.1, ACH92248.1, CAB66144.1, AGB96135.1, AFH06520.1, AFH06522.2, AFH06521.1
Gene_ORFName: CG43122, CG43122, Dmel_CG43122, Dmel_CG43122, CG43122, Dmel_CG43122, CG43122, Dmel_CG43122, CG43122
EnsemblGenome_TRS: FBtr0305027, FBtr0305026, FBtr0334305, FBtr0305028, FBtr0334306, FBtr0305029
Protein sequencees
EnsemblGenome_PRO: FBpp0293563, FBpp0293564, FBpp0306420, FBpp0293565, FBpp0306421, FBpp0293566
RefSeq: NP_001262755.1, NP_001247204.2, NP_001247203.1, NP_001097843.1, NP_524992.1, NP_001247202.1
Others
UniRef100: UniRef100_A0A0B4K698, UniRef100_Q9U1H0, UniRef100_A0A0B4K778, UniRef100_A0A0B4KGD7
UniRef90: UniRef90_Q9U1H0, UniRef90_Q9U1H0-2, UniRef90_A0A0B4K698
UniRef50: UniRef50_Q9U1H0, UniRef50_A0A0B4K698, UniRef50_Q9U1H0-2
UniGene: Dm.5727

全选

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