| Type | Description |
|---|---|
| Definition | perilipin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:46:00 | High prevalence of mutations in perilipin 1 in patients with precocious acute coronary syndrome. | 31877397 |
| 2020-05-30 13:17:00 | Identification of two heterozygous PLIN1 frameshift variants segregating with the phenotype in nine patients from four unrelated families. The Familial partial lipodystrophy 4 stereotypical signs included postpubertal partial lipoatrophy of variable severity, muscular hypertrophy, acromegaloid features, polycystic ovary syndrome and/or hirsutism, metabolic complications. | 31504636 |
| 2020-03-14 12:41:00 | perilipin 1 is a promising marker for the differential diagnosis of liposarcomas from other soft tissue sarcomas, whereas perilipin 2 correlates negatively with tumor grade and may be therapeutically useful. | 31125552 |
| 2019-11-23 10:15:00 | Studied physiology of weight loss through gene expression of uncoupling protein 3(UCP3), perilipin 1 (PLIN1), and peroxisome proliferator activated receptor gamma (PPARG2) in obese female patients after low calorie diet intervention. With hypocaloric diet, found UCP3 reduced in obese patients and UCP3, PLIN1 and PPARG2 correlate positively with carbohydrate oxidation and negatively with lipid oxidation. | 28651828 |
| 2019-07-13 11:49:00 | Data indicate that perilipin 1 (PLIN1) specifically binds to cholesteryl esters, and that their dynamic properties direct segregation of perilipin 1 into topologically distinct micro domains on the lipid droplet. | 29118433 |
| Type | IDs |
|---|---|
| Synonymous | FPLD4, PERI, PLIN |
| Gene |
UniProtKB-ID:
PLIN1_HUMAN
UniprotKB:
O60240
UniParc:
UPI000013E61C
EMBL:
BC031084,
AC013787,
AB005293
Ensembl:
ENSG00000166819
KO:
hsa:5346
|
| Nucleutide sequences |
EMBL-CDS:
AAH31084.1,
BAA25420.1
Ensembl_TRS:
ENST00000430628,
ENST00000300055
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402167,
ENSP00000300055
RefSeq:
NP_001138783.1,
NP_002657.3,
XP_005254991.1
|
| Others |
UniRef100:
UniRef100_O60240
UniRef90:
UniRef90_O60240
UniRef50:
UniRef50_O60240
UniGene:
Hs.103253
CCDS:
CCDS10353.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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