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53442 Spt5

53442

Spt5

Spt5

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Spt5

研究结论

Date Results Publications
2018-03-10 11:26:00 Mutation in the protein-protein interaction domain (REPO domain) of Pho interferes with the dynamics of its interaction with Spt5. The transcriptional kinetics of the heat shock response is negatively affected by a mutation in the REPO domain of Pho 29208012
2017-06-24 10:12:00 KOW5 is involved in promoter-proximal pausing through contact with the nascent RNA 28213523
2014-03-01 10:11:00 Spt5 interacts both physically and genetically with the Polycomb Group (PcG) protein Pleiohomeotic (Pho) 23894613
2013-05-18 11:05:00 We show that SPT5 interacts directly with MSL1 in vitro and is required downstream of MSL complex recruitment, providing the first mechanistic data corroborating the elongation model of dosage compensation. 23209435
2010-01-21 00:00:00 Spt5 acts both positively and negatively on transcription in vivo during heat shock induction. 15380072

名称对应

Type IDs
Synonymous CG7626, DSIF, Dmel\CG7626, Dspt5, SPT5, dDSIF, dSpt5, spt5
Gene
UniProtKB-ID: SPT5H_DROME
UniprotKB: Q9V460
UniParc: UPI0000082ACB, UPI0000085115
EMBL: AE013599, AF222864, AY069140, BT023840, BT001668
EnsemblGenome: FBgn0040273
KO: dme:Dmel_CG7626
Nucleutide sequences
EMBL-CDS: AAF57561.1, AAL39285.1, AAZ86761.1, AAF34689.1, AAN71423.1
Gene_ORFName: CG7626
EnsemblGenome_TRS: FBtr0086531
Protein sequencees
EnsemblGenome_PRO: FBpp0085716
RefSeq: NP_652610.1
Others
UniRef100: UniRef100_Q9V460
UniRef90: UniRef90_Q9V460
UniRef50: UniRef50_Q9V460
UniGene: Dm.2263

全选

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研究热度

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