| Type | Description |
|---|---|
| Definition | von Hippel-Lindau |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K). | 31959630 |
| 2019-03-02 10:51:00 | In both models, L- as well as D-arginine enhanced the ability of wild-type pVHL and certain misfolded mutant versions of pVHL to bind ODD, the HIF-derived target peptide, reflecting restoration of pVHL function. Moreover, continuous feeding of Drosophila expressing misfolded versions of pVHL either L- or D-arginine rich diet rescued their lethal phenotype. | 30194449 |
| 2015-10-03 10:24:00 | Interaction between Nm23 and the tumor suppressor VHL | 24915993 |
| 2015-09-26 19:34:00 | Transgenic pVHL can fully maintain normal dVHL-HIF1-alpha downstream pathways in flies. | 25310726 |
| 2012-06-09 11:23:00 | Codepletion of Vhl with Mgr gives partial rescue of tubulin instability, monopolar spindle formation, and loss of centrosomes. | 22451918 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:RH61560, CG13221, DVhl, Dmel\CG13221, Dvhl, VHL, d-VHL, d-vhl, dVHL, dmVHL, vhl |
| Gene |
UniProtKB-ID:
VHL_DROME,
A0A0B4KEJ4_DROME
UniprotKB:
Q9V3C1,
A0A0B4KEJ4
UniParc:
UPI0000083ED7
EMBL:
AF195836,
AE013599,
BT023867,
AY075555
EnsemblGenome:
FBgn0041174
KO:
dme:Dmel_CG13221
|
| Nucleutide sequences |
EMBL-CDS:
AAF58684.1,
AAZ86788.1,
AAF29377.1,
AAL68362.1,
AGB93418.1
Gene_ORFName:
CG13221,
Dmel_CG13221,
CG13221
EnsemblGenome_TRS:
FBtr0332420,
FBtr0088115,
FBtr0332420,
FBtr0088115
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0304693,
FBpp0087216,
FBpp0087216,
FBpp0304693
RefSeq:
NP_001260885.1,
NP_524986.1
|
| Others |
UniRef100:
UniRef100_Q9V3C1
UniRef90:
UniRef90_Q9V3C1
UniRef50:
UniRef50_Q9V3C1
UniGene:
Dm.20362
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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