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53413 Exoc7

53413

Exoc7

exocyst complex component 7

protein-coding

Mus musculus

基因描述

Type Description
Definition exocyst complex component 7

研究结论

Date Results Publications
2020-06-27 11:56:00 Insulin-stimulated GLUT4 exocytosis was markedly inhibited in Exoc7 KO adipocytes. 31740584
2020-05-16 12:22:00 Here we show that microtubule stabilization, triggered by engagement of the B cell receptor, acts as a cue to release centrosome-associated Exo70, which is redistributed to the immune synapse. This process is coupled to the recruitment and activation of GEF-H1, which is required for assembly of the exocyst complex, used to promote tethering and fusion of lysosomes at the immune synapse. 31197029
2013-11-02 11:43:00 Exo70 thus represents a membrane-bending protein that may couple actin dynamics and plasma membrane remodeling for morphogenesis. 23948253
2010-01-21 00:00:00 Given the low level of sequence conservation within Exo70, this structure provides new insights into our understanding of many species-specific functions of the exocyst 17583731
2010-01-21 00:00:00 Results show that Snapin interacts with the exocyst Exo70 and plays a modulatory role in GLUT4 vesicle trafficking. 17947242

名称对应

Type IDs
Synonymous Exo70, sec70
Gene
UniProtKB-ID: EXOC7_MOUSE, Q542L0_MOUSE, A2AAN0_MOUSE, Q3USE0_MOUSE
UniprotKB: O35250, Q542L0, A2AAN0, Q3USE0
UniParc: UPI0000004185, UPI000059DDF6, UPI0000021A18
EMBL: BC028927, AK140450, AF014461, AK169928, AK087601, AL645861
Ensembl: ENSMUSG00000020792
KO: mmu:53413
Nucleutide sequences
EMBL-CDS: AAB69345.1, AAH28927.1, BAE41466.1, BAC39941.1, BAE24393.1
Ensembl_TRS: ENSMUST00000106411, ENSMUST00000021147, ENSMUST00000106413
Protein sequencees
Ensembl_PRO: ENSMUSP00000102019, ENSMUSP00000021147, ENSMUSP00000102021
RefSeq: NP_001349768.1, NP_001349767.1, NP_058553.2, NP_001365889.1, NP_001365890.1, XP_006533797.1, NP_001156344.1, NP_001334565.1
Others
UniRef100: UniRef100_Q542L0, UniRef100_O35250, UniRef100_A2AAN0
UniRef90: UniRef90_A0A286X875, UniRef90_O35250
UniRef50: UniRef50_Q9UPT5
UniGene: Mm.22530
CCDS: CCDS25664.1, CCDS48983.1

全选

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