| Type | Description |
|---|---|
| Definition | chloride intracellular channel 5 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 10:06:00 | loss of ETV6 leads to significant overexpression of CLIC5, which in turn leads to decreased lysosome-mediated apoptosis. Our data suggest that heightened CLIC5 activity could promote a permissive environment for oxidative stress-induced DNA damage accumulation, and thereby contribute to leukemogenesis. | 27540136 |
| 2016-04-23 10:43:00 | EZR, CLIC5 and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness | 26135398 |
| 2015-11-21 10:23:00 | The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling. | 25344252 |
| 2015-10-03 11:31:00 | CLIC5 is a novel gene involved in progressive hearing impairment, vestibular and possibly mild renal dysfunction. | 24781754 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | DFNB102, DFNB103, MST130, MSTP130 |
| Gene |
UniProtKB-ID:
CLIC5_HUMAN,
Q49AE1_HUMAN,
Q53G01_HUMAN
UniprotKB:
Q9NZA1,
Q49AE1,
Q53G01
UniParc:
UPI000056F1A1,
UPI000006E025,
UPI000013C5ED,
UPI000002A6AF
EMBL:
DQ679794,
BC035968,
AK222544,
AL357057,
AK223130,
AF216941,
AK097048,
CH471081,
AL355522,
AY032602,
AL591211,
BC039380,
AK075163,
AL050336,
AK075144
Ensembl:
ENSG00000112782
KO:
hsa:53405
|
| Nucleutide sequences |
EMBL-CDS:
AAF66928.1,
EAX04287.1,
AAH35968.1,
BAC11432.1,
BAG53413.1,
EAX04286.1,
BAC11444.1,
AAK52083.1,
AAH39380.1,
ABG46342.1,
BAD96264.1,
EAX04285.1,
BAD96850.1
Gene_ORFName:
hCG_2001062
Ensembl_TRS:
ENST00000185206,
ENST00000544153,
ENST00000339561
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439195,
ENSP00000185206,
ENSP00000344165
RefSeq:
XP_011512996.1,
NP_001357578.1,
NP_001357579.1,
NP_001242952.1,
NP_001107558.1,
NP_058625.2,
XP_011512994.1
|
| Others |
UniRef100:
UniRef100_A0A2J8Y519,
UniRef100_Q49AE1,
UniRef100_Q9NZA1
UniRef90:
UniRef90_Q49AE1,
UniRef90_Q9NZA1,
UniRef90_G1QTT1
UniRef50:
UniRef50_Q49AE1,
UniRef50_Q9NZA1,
UniRef50_Q8BXK9
UniGene:
Hs.485489,
Hs.734348
CCDS:
CCDS59022.1,
CCDS47438.1,
CCDS4914.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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