| Type | Description |
|---|---|
| Definition | phospholipase C beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Phospholipase C controls chloride-dependent short-circuit current in human bronchial epithelial cells. | 33236921 |
| 2020-08-22 15:27:00 | Intramolecular electrostatic interactions contribute to phospholipase Cbeta3 autoinhibition. | 31254604 |
| 2019-09-14 12:16:00 | A homozygous loss of function variant in PLCB3 is associated with corneal dystrophy, developmental delay and spondylometaphyseal dysplasia. | 29122926 |
| 2019-04-20 12:10:00 | These results, besides identifying S845L as a loss-of-function variant, strengthen the importance of targeting PLCB3 to mitigate the cystic fibrosis inflammatory response in bronchial epithelial cells without blunting the immune response. | 29668297 |
| 2019-03-23 12:12:00 | This study reveals detailed mechanistic insight into the role of ORP4L in PLCbeta3 redistribution from storage within the nucleus to the plasma membrane via RAN activation and interaction with VAPA in Jurkat T-cells. | 30237164 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PLCB3_HUMAN
UniprotKB:
Q01970
UniParc:
UPI0000131AFF,
UPI00001415D7
EMBL:
Z37564,
Z37555,
Z37548,
Z37571,
Z37557,
Z37554,
Z37544,
CH471076,
BC142681,
AP001453,
Z37560,
Z37569,
Z37566,
Z37553,
Z37562,
Z37565,
Z37568,
Z37559,
Z37549,
Z37573,
Z16411,
Z37561,
BC032659,
Z37551,
Z37567,
Z37552,
Z37558,
Z37547,
Z37556,
Z37570,
Z37572,
Z37546,
Z37550,
Z37574,
U26425,
Z37545
Ensembl:
ENSG00000149782
KO:
hsa:5331
|
| Nucleutide sequences |
EMBL-CDS:
CAA78903.1,
EAW74231.1,
AAH32659.1,
EAW74230.1,
AAA77683.1,
CAA85776.1,
AAI42682.1
Ensembl_TRS:
ENST00000325234,
ENST00000540288,
ENST00000279230
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000279230,
ENSP00000324660,
ENSP00000443631
RefSeq:
NP_001171812.1,
NP_001303243.1,
XP_016873414.1,
XP_011543403.1,
NP_000923.1
|
| Others |
UniRef100:
UniRef100_Q01970
UniRef90:
UniRef90_Q01970
UniRef50:
UniRef50_Q01970
UniGene:
Hs.523761
CCDS:
CCDS8064.1,
CCDS53654.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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