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5319 PLA2G1B

5319

PLA2G1B

phospholipase A2 group IB

protein-coding

Homo sapiens

基因描述

Type Description
Definition phospholipase A2 group IB

研究结论

Date Results Publications
2021-02-06 13:54:00 PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients. 32436864
2018-09-29 11:03:00 sPLA2-IB was correlated with the level of proteinuria in membranous nephropathy patients suggesting to be a potential biomarker for monitoring disease severity and therapeutic effects of both primary membranous nephropathy and secondary membranous nephropathy. 29649452
2015-10-31 10:37:00 The sPLA2 IB-PLA2R interaction stimulated podocyte apoptosis through activating ERK1/2 and cPLA2alpha and through increasing the podocyte AA content 25335547
2014-05-17 15:40:00 TNF-alpha-induced cPLA2 expression and PGE2 release were mediated through a Jak2/PDGFR/PI3K/Akt/p42/p44 MAPK/Elk-1 pathway in human lung epithelial cells. 24441870
2013-01-26 11:15:00 Exogenously added sPLA(2)-IB decreases phagocytosis of photoreceptor outer segments regardless of enzymatic activity. 22680611

名称对应

Type IDs
Synonymous PLA2, PLA2A, PPLA2
Gene
UniProtKB-ID: PA21B_HUMAN
UniprotKB: P04054
UniParc: UPI0000048FD9
EMBL: M21056, BC106726, CH471054, BC106725, AY438977, AK311830, M21054, M22970, AC003982
Ensembl: ENSG00000170890
KO: hsa:5319
Nucleutide sequences
EMBL-CDS: AAI06726.1, AAR05441.1, BAG34772.1, AAA36450.1, EAW98184.1, AAI06727.1, AAB95635.1, AAA60107.1
Ensembl_TRS: ENST00000308366
Protein sequencees
Ensembl_PRO: ENSP00000312286
RefSeq: NP_000919.1
Others
UniRef100: UniRef100_P04054
UniRef90: UniRef90_P04054
UniRef50: UniRef50_P04054
UniGene: Hs.992
CCDS: CCDS9195.1

全选

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研究热度

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