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5316 PKNOX1

5316

PKNOX1

PBX/knotted 1 homeobox 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition PBX/knotted 1 homeobox 1

研究结论

Date Results Publications
2021-01-09 13:33:00 Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. 33033354
2019-11-02 11:54:00 These data implicate the upregulated hepatic expression of Pknox1 in type 2 diabetes mellitus (T2DM) complicated with nonalcoholic fatty liver disease (NAFLD) may be caused by the reduced expression of miR-17 family, indicating that developing miRNA-mediated regulation strategies on Pknox1 may provide new therapeutic options for metabolic disease 30338914
2019-10-19 11:34:00 the replication timing of a specific fraction of the human genome is affected by PREP1 tumor suppressor 29453404
2015-04-25 10:21:00 PREP1 modulates the cellular sensitivity to TGF-beta by inducing the small mothers against decapentaplegic homolog 3 (SMAD3) nuclear translocation. 25157139
2012-08-18 10:39:00 High levels of MEIS1 and PREP1, and low levels of PBX4 expression were founded in samples of patients with ALL. 22185299

名称对应

Type IDs
Synonymous PREP1, pkonx1c
Gene
UniProtKB-ID: PKNX1_HUMAN, E7EPN6_HUMAN, B4DGV5_HUMAN, Q96I87_HUMAN, Q6PKH2_HUMAN
UniprotKB: P55347, E7EPN6, B4DGV5, Q96I87, Q6PKH2
UniParc: UPI00001BD8DF, UPI000000D8D4, UPI0000074479, UPI00017A6EC2, UPI0002064F79
EMBL: Y13613, U68727, BC000735, BC007746, AP001630, AK294794, AP001748, CH471079, AY196965, AY142115
Ensembl: ENSG00000160199
KO: hsa:5316
Nucleutide sequences
EMBL-CDS: BAA95533.1, AAN34940.1, AAC51243.1, CAA73934.1, BAG57916.1, EAX09518.1, AAH07746.1, AAO45825.1, AAH00735.1
Gene_ORFName: hCG_2043122
Ensembl_TRS: ENST00000291547, ENST00000432907
Protein sequencees
Ensembl_PRO: ENSP00000291547, ENSP00000402243
RefSeq: NP_004562.2, NP_001307623.1, NP_001273187.1
Others
UniRef100: UniRef100_P55347, UniRef100_Q6PKH2, UniRef100_B4DGV5
UniRef90: UniRef90_Q6PKH2, UniRef90_A0A494BB27, UniRef90_P55347
UniRef50: UniRef50_Q7SYL8, UniRef50_Q96KN3-2, UniRef50_Q6PKH2
UniGene: Hs.431043
CCDS: CCDS13692.1

全选

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