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5315 PKM

5315

PKM

pyruvate kinase M1/2

protein-coding

Homo sapiens

基因描述

Type Description
Definition pyruvate kinase M1/2

研究结论

Date Results Publications
2021-04-13 10:14:00 Citrullination of pyruvate kinase M2 by and regulates glycolysis and cancer cell proliferation. 33741961
2021-04-13 10:09:00 HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma. 33279948
2021-04-03 13:37:00 Overexpression of Pyruvate Kinase M2 in Tumor Tissues Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma. 30852741
2021-04-03 13:35:00 Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation. 33453989
2021-03-20 13:29:00 A novel miR-206/hnRNPA1/PKM2 axis reshapes the Warburg effect to suppress colon cancer growth. 32800545

名称对应

Type IDs
Synonymous CTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1
Gene
UniProtKB-ID: KPYM_HUMAN, V9HWB8_HUMAN, A0A024R5Z9_HUMAN, B4DNK4_HUMAN
UniprotKB: P14618, V9HWB8, A0A024R5Z9, B4DNK4
UniParc: UPI0000169DBC, UPI000014064D, UPI00017A7FFA, UPI00017A78BA
EMBL: AY352517, EU794631, CH471082, BC007952, AK222927, BC012811, AK297951, BC000481, BC007640, AF025439, AK092369, M23725, M26252, AC020779, AK300800, BC035198, AK312253, X56494, AK294315
Ensembl: ENSG00000067225
KO: hsa:5315
Nucleutide sequences
EMBL-CDS: BAG62458.1, AAA36672.1, EAW77888.1, AAC39559.1, BAG57589.1, AAH00481.3, BAD96647.1, EAW77884.1, AAH12811.3, AAH07952.3, AAH35198.1, AAQ15274.1, CAA39849.1, AAA36449.1, BAG52542.1, BAG35185.1, AAH07640.1, ACJ13685.1, EAW77890.1, BAG60266.1
Gene_ORFName: hCG_2005199
Ensembl_TRS: ENST00000319622, ENST00000565184, ENST00000565154, ENST00000568459, ENST00000449901, ENST00000335181, ENST00000389093
Protein sequencees
Ensembl_PRO: ENSP00000455901, ENSP00000456970, ENSP00000403365, ENSP00000455736, ENSP00000334983, ENSP00000320171, ENSP00000373745
RefSeq: NP_001193726.1, XP_006720633.1, NP_872271.1, NP_002645.3, XP_005254502.1, NP_001193727.1, XP_011519972.1, XP_005254500.1, NP_872270.1, XP_016877802.1, NP_001193728.1, NP_001303247.1, NP_001193725.1
Others
UniRef100: UniRef100_B4DNK4, UniRef100_P14618, UniRef100_A0A024R5Z9
UniRef90: UniRef90_P14618, UniRef90_A0A1D5R021
UniRef50: UniRef50_P14618, UniRef50_P22360
UniGene: Hs.534770
CCDS: CCDS32284.1, CCDS32285.1, CCDS55972.1

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