| Type | Description |
|---|---|
| Definition | polycystin 1, transient receptor potential channel interacting |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus. | 33164752 |
| 2021-03-13 13:16:00 | TSC2/PKD1 contiguous gene syndrome, with emphasis on a case with an atypical mild polycystic kidney phenotype and a novel genetic variant. | 31176519 |
| 2021-01-16 15:55:00 | Polycystin-1 induces activation of the PI3K/AKT/mTOR pathway and promotes angiogenesis in renal cell carcinoma. | 32561414 |
| 2020-12-12 13:28:00 | Mutational screening of PKD1 and PKD2 in Indian ADPKD patients identified 95 genetic variants. | 32823016 |
| 2020-12-12 13:26:00 | Angiogenin regulates PKD activation and COX-2 expression induced by TNF-alpha and bradykinin in the colonic myofibroblast. | 32171525 |
| Type | IDs |
|---|---|
| Synonymous | PBP, PC1, Pc-1, TRPP1 |
| Gene |
UniProtKB-ID:
PKD1_HUMAN
UniprotKB:
P98161
UniParc:
UPI0000212762,
UPI0001AE79C2,
UPI00001B0454
EMBL:
L43605,
AC009065,
U24497,
L43618,
L43602,
AC093513,
L43610,
L43619,
L33243,
L43617,
L43601,
L43604
Ensembl:
ENSG00000008710
KO:
hsa:5310
|
| Nucleutide sequences |
EMBL-CDS:
AAC37576.1,
AAC50128.1,
AAC41765.1
Ensembl_TRS:
ENST00000262304,
ENST00000423118
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399501,
ENSP00000262304
RefSeq:
NP_000287.4,
XP_005255427.1,
XP_024306068.1,
XP_011520830.1,
XP_024306067.1,
XP_024306069.1,
NP_001009944.3,
XP_024306066.1,
XP_011520839.1,
XP_011520831.1
|
| Others |
UniRef100:
UniRef100_P98161
UniRef90:
UniRef90_P98161
UniRef50:
UniRef50_P98161
UniGene:
Hs.75813
CCDS:
CCDS45385.1,
CCDS32369.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员