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5303 PIN4

5303

PIN4

peptidylprolyl cis/trans isomerase, NIMA-interacting 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition peptidylprolyl cis/trans isomerase, NIMA-interacting 4

研究结论

Date Results Publications
2019-11-23 12:23:00 In the presence of HBx, the Par14 and Par17 proteins bound to cccDNA. 30567987
2019-06-01 10:53:00 Numerous other proteins in addition to PIN1 are endowed with PPIase activity. These include other members of the parvulin family to which PIN1 belongs, such as PIN4, as well as several cyclophilins and FK506-binding proteins...This review will discuss studies providing evidence for multiple roles of PIN1 and other PPIases in glioblastoma and medulloblastoma, the most frequent adult and pediatric primary brain tumors. 30314361
2016-01-30 11:36:00 Par14 can be described as an endogenous non-histone chromatin protein, which binds DNA in vivo 25645591
2015-10-31 11:04:00 Ca(2+)/Calmodulin binding to the N-terminal of Par17 causes steric hindrance of the Par17 active site, thus interfering with the Par17/tubulin interaction. 25940090
2015-10-03 10:17:00 Data indicate that Pin1 prolyl isomerase active site cysteine, Cys113, is highly susceptible to oxidation. 25595659

名称对应

Type IDs
Synonymous EPVH, PAR14, PAR17
Gene
UniProtKB-ID: PIN4_HUMAN
UniprotKB: Q9Y237
UniParc: UPI00002263A9, UPI0001C0B3B6, UPI0000131AF2
EMBL: AL135749, BC070288, AB009690, AF143096, BC112281, AK127605, BX119917, BC005234, BC111394, BC093700, AM420633, BC104653
Ensembl: ENSG00000102309
KO: hsa:5303
Nucleutide sequences
EMBL-CDS: AAH93700.1, AAI04654.1, CAM12362.1, AAI12282.1, AAD27893.1, BAA82320.1, AAH05234.2, AAH70288.1, AAI11395.1, BAG54532.1
Ensembl_TRS: ENST00000423432, ENST00000373669, ENST00000664196
Protein sequencees
Ensembl_PRO: ENSP00000409154, ENSP00000362773, ENSP00000499466
RefSeq: NP_006214.3, NP_001164218.1
Others
UniRef100: UniRef100_Q9Y237
UniRef90: UniRef90_Q9Y237
UniRef50: UniRef50_Q9Y237
UniGene: Hs.655623
CCDS: CCDS14417.1, CCDS55447.1

全选

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