| Type | Description |
|---|---|
| Definition | acid phosphatase 2, lysosomal |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 10:45:00 | In addition to replicating a previously identified genome-wide significant locus for corneal astigmatism near the PDGFRA gene, gene-based analysis identified three novel candidate genes, CLDN7, ACP2, and TNFAIP8L3, that warrant further investigation to understand their role in the pathogenesis of corneal astigmatism. (Meta-analysis) | 29422769 |
| 2017-08-12 10:58:00 | Data show that lysosomal acid phosphatase 2 (ACP2) was overexpressed in colorectal cancer (CRC) and associated with poor outcome in stage II CRC, and that high expression of ACP2 patients were more sensitive to chemotherapy than those with a low expression, suggesting ACP2 as a marker for CRC patients receiving chemotherapy. | 28076332 |
| 2014-10-22 10:27:00 | An enzymatically inactive allele of mouse Acp2 causes cerebellum abnormalities, growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. | 15503243 |
| 2014-10-22 10:26:00 | LAP-deficient mice exhibit multiple defects including bone structure alterations, lysosomal storage defects in the kidneys and central nervous system, and an increased tendency towards seizures. | 9228031 |
| 2009-09-20 21:33:00 | Observational study of gene-disease association. (HuGE Navigator) | 19064571 |
| Type | IDs |
|---|---|
| Synonymous | LAP |
| Gene |
UniProtKB-ID:
PPAL_HUMAN,
E9PHY0_HUMAN,
B7Z6T8_HUMAN,
B7Z6L8_HUMAN,
E9PQY3_HUMAN,
B7Z4Z2_HUMAN,
B7Z8T9_HUMAN,
B7Z7D2_HUMAN,
B7Z552_HUMAN
UniprotKB:
P11117,
E9PHY0,
B7Z6T8,
B7Z6L8,
E9PQY3,
B7Z4Z2,
B7Z8T9,
B7Z7D2,
B7Z552
UniParc:
UPI00019152C0,
UPI0000131FE1,
UPI0001915089,
UPI0001914E59,
UPI0001F77D18,
UPI0001915191,
UPI0001F77D1A,
UPI00017C1448,
UPI0001915044,
UPI0001915282
EMBL:
AK298439,
X15531,
DA382854,
X15525,
AK303894,
X15529,
X15534,
X15530,
AK301860,
AK300569,
X15532,
BC093010,
X15535,
X15533,
X15526,
X15528,
AC018410,
X15527,
AK298122,
AK300911,
BC003160,
X12548
Ensembl:
ENSG00000134575
KO:
hsa:53
|
| Nucleutide sequences |
EMBL-CDS:
CAA33542.1,
AAH03160.1,
AAH93010.1,
CAA31064.1,
BAH13374.1,
BAH13304.1,
BAH12728.1,
BAH14075.1,
BAH13568.1,
BAH12788.1
Ensembl_TRS:
ENST00000672073,
ENST00000256997,
ENST00000529444,
ENST00000533929,
ENST00000527256
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000256997,
ENSP00000500291,
ENSP00000436658,
ENSP00000432439,
ENSP00000432205
RefSeq:
NP_001289418.1,
NP_001289421.1,
NP_001343945.1,
NP_001289419.1,
NP_001289420.1,
NP_001601.1
|
| Others |
UniRef100:
UniRef100_E9PQY3,
UniRef100_B7Z552,
UniRef100_E9PHY0,
UniRef100_B7Z8T9,
UniRef100_P11117,
UniRef100_A0A2J8WF00,
UniRef100_B7Z4Z2,
UniRef100_B7Z7D2,
UniRef100_B7Z6L8
UniRef90:
UniRef90_E2RS03,
UniRef90_U6D1P2,
UniRef90_P11117,
UniRef90_Q5NVF6,
UniRef90_B7Z6U3
UniRef50:
UniRef50_Q0P5F0,
UniRef50_P20611,
UniRef50_P11117-2,
UniRef50_P11117,
UniRef50_U6D1P2
UniGene:
Hs.532492
CCDS:
CCDS7928.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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