| Type | Description |
|---|---|
| Definition | phosphatidylinositol 4-kinase alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 10:17:00 | we provide evidence linking PI4KAP2, previously considered a pseudogene, to human myeloid and erythroid leukemia. | 29386109 |
| 2018-07-14 10:45:00 | Architecture of the human PI4KIIIalpha lipid kinase complex. | 29229838 |
| 2017-08-12 10:16:00 | hCKalpha functions as an indispensable regulator that bridges PI4KIIIalpha and hepatitis C virus NS5A and potentiates NS5A-stimulated PI4KIIIalpha activity, which then facilitates the targeting of the ternary complex to the endoplasmic reticulum for viral replication. | 28566381 |
| 2017-06-03 12:13:00 | Blockade of IQGAP1 interaction with PIPKIalpha or PI(3)K inhibited PtdIns(3,4,5)P3 generation and signalling, and selectively diminished cancer cell survival. | 27870828 |
| 2017-05-13 14:54:00 | The results showed that, in contrast to the enteroviruses and the cardioviruses, foot-and-mouth disease virus replication does not require PI4KIII (PI4KIIIalpha and PI4KIIIbeta), and phosphatidylinositol 4-phosphate levels do not increase in foot-and-mouth disease virus-infected cells and phosphatidylinositol 4-phosphate is not seen at replication organelles. | 27093462 |
| Type | IDs |
|---|---|
| Synonymous | PI4K-ALPHA, PIK4CA, PMGYCHA, pi4K230 |
| Gene |
UniProtKB-ID:
PI4KA_HUMAN,
B4DYG5_HUMAN,
Q4LE69_HUMAN
UniprotKB:
P42356,
B4DYG5,
Q4LE69
UniParc:
UPI0000E06BD6,
UPI00017A82CE,
UPI0000131A88,
UPI000054C914
EMBL:
AK302424,
AC007050,
BC053654,
AC007308,
L36151,
BC018120,
AB210002,
AF012872
Ensembl:
ENSG00000241973
KO:
hsa:5297
|
| Nucleutide sequences |
EMBL-CDS:
AAD13352.1,
AAA56839.1,
AAH18120.2,
AAH53654.1,
BAG63727.1,
BAE06084.1
Ensembl_TRS:
ENST00000255882
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255882
RefSeq:
XP_011528530.1,
XP_011528528.1,
NP_001349791.1,
XP_005261692.1,
XP_016884319.1,
NP_001349792.1,
NP_477352.3
|
| Others |
UniRef100:
UniRef100_P42356,
UniRef100_B4DYG5
UniRef90:
UniRef90_P42356
UniRef50:
UniRef50_P42356
UniGene:
Hs.529438,
Hs.731386
CCDS:
CCDS33603.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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