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5296 PIK3R2

5296

PIK3R2

phosphoinositide-3-kinase regulatory subunit 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphoinositide-3-kinase regulatory subunit 2

研究结论

Date Results Publications
2020-12-26 13:12:00 PIK3R2/Pik3r2 Activating Mutations Result in Brain Overgrowth and EEG Changes. 32856318
2020-08-13 18:51:00 p85beta regulates autophagic degradation of AXL to activate oncogenic signaling. 32385243
2020-06-13 10:55:00 Findings provided evidence that downregulation of miR-135a inhibits proliferation, migration, and invasion and promotes apoptosis of synovial fibroblasts in rheumatoid arthritis by upregulating PIK3R2 coupled with inactivating the PI3K/AKT signaling pathway. 30912120
2020-02-08 10:36:00 USP49 inhibits non-small cell lung cancer cell growth by suppressing PIK3R2/AKT signaling. 31001918
2018-03-24 12:04:00 Data indicate that miR-126 overexpression in RASFs inhibits PIK3R2 expression and promotes proliferation while inhibiting apoptosis. 27729613

名称对应

Type IDs
Synonymous MPPH, MPPH1, P85B, p85, p85-BETA
Gene
UniProtKB-ID: P85B_HUMAN
UniprotKB: O00459
UniParc: UPI000006EF95
EMBL: AC007192, BC070082, X80907, BC090249
Ensembl: ENSG00000105647
KO: hsa:5296
Nucleutide sequences
EMBL-CDS: CAA56868.1, AAH90249.1, AAH70082.1, AAD22671.1
Ensembl_TRS: ENST00000617130, ENST00000222254
Protein sequencees
Ensembl_PRO: ENSP00000477864, ENSP00000222254
RefSeq: NP_005018.2
Others
UniRef100: UniRef100_O00459
UniRef90: UniRef90_O00459
UniRef50: UniRef50_O00459
UniGene: Hs.371344
CCDS: CCDS12371.1

全选

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研究热度

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