| Type | Description |
|---|---|
| Definition | regulator of G-protein signalling 7 binding protein |
| Date | Results | Publications |
|---|---|---|
| 2017-04-29 10:12:00 | The results of this study indicated that R7bp is a key regulator of itch sensation and suggest the potential targeting of R7bp-dependent GTPase activating protein activity as a novel therapeutic strategy for pathological itch | 28134655 |
| 2016-11-05 12:02:00 | R7-binding protein had a strong inhibitory effect on homo-oligomerization of RGS7. | 26895961 |
| 2014-10-18 10:19:00 | R7BP-dependent regulation of R7-RGS proteins shapes specific aspects of light-evoked and spontaneous activity of retinal ganglion cells in mature and developing retina. | 24349243 |
| 2013-02-09 11:38:00 | GIRK modulation occurs by channel assembly with R7-RGS/Gbeta5 complexes under allosteric control of R7 RGS-binding protein (R7BP). | 23169654 |
| 2012-11-24 11:21:00 | R7BP is a negative modulator of the analgesic and locomotor activating actions of morphine that contributes to the development of morphine tolerance. | 22089315 |
| Type | IDs |
|---|---|
| Synonymous | A930030I01Rik, AI842293, D13Bwg1146e, R7bp |
| Gene |
UniProtKB-ID:
R7BP_MOUSE
UniprotKB:
Q8BQP9
UniParc:
UPI00000EAF08
EMBL:
DQ104214,
AK036240,
BC118957,
AK137417,
AK020910,
AK046733
Ensembl:
ENSMUSG00000021719
KO:
mmu:52882
|
| Nucleutide sequences |
EMBL-CDS:
AAI18958.1,
BAC29358.1,
AAZ09201.1,
BAE23346.1,
BAC32849.1,
BAB32250.1
Ensembl_TRS:
ENSMUST00000063551
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000066614
RefSeq:
NP_084155.2,
XP_006517785.1
|
| Others |
UniRef100:
UniRef100_Q8BQP9
UniRef90:
UniRef90_Q8BQP9
UniRef50:
UniRef50_Q8BQP9
UniGene:
Mm.100348
CCDS:
CCDS36774.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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