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52864 Slx4

52864

Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

protein-coding

Mus musculus

基因描述

Type Description
Definition SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

研究结论

Date Results Publications
2015-04-18 11:01:00 Data shed light on SLX4 recruitment, and they point to the existence of currently unidentified ubiquitylated ligands and E3 ligases that are crucial for ICL repair. 24794496
2014-07-26 11:18:00 SLX4 is a tumor suppressor, which activates XPF-ERCC1 nuclease specificity in DNA crosslink repair. 24726326
2014-01-18 10:44:00 Data indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4. 24076219
2011-10-01 12:07:00 these data indicate that BTBD12 functions throughout gametogenesis to maintain genome stability, possibly by co-ordinating repair processes and/or by linking DNA repair events to the cell cycle via ATM 21655083
2011-04-02 10:04:00 mouse Slx4, a regulator of structure-specific nucleases, disruption phenocopies Fanconi anemia 21240276

名称对应

Type IDs
Synonymous AI256635, AI426760, Btbd12, D16Bwg1016e
Gene
UniProtKB-ID: SLX4_MOUSE
UniprotKB: Q6P1D7
UniParc: UPI000023B717
EMBL: BC065125
Ensembl: ENSMUSG00000039738
KO: mmu:52864
Nucleutide sequences
EMBL-CDS: AAH65125.1
Ensembl_TRS: ENSMUST00000040790
Protein sequencees
Ensembl_PRO: ENSMUSP00000038871
RefSeq: XP_030105043.1, XP_036015903.1, XP_030105047.1, XP_006522416.1, XP_006522422.1, XP_036015901.1, XP_036015900.1, XP_030105038.1, XP_030105037.1, XP_017172557.1, XP_030105041.1, XP_030105046.1, XP_006522418.1, XP_036015902.1, XP_030105039.1, XP_006522415.1, NP_803423.2, XP_006522413.1, XP_030105042.1, XP_006522417.1, XP_030105045.1, XP_006522412.1, XP_036015899.1
Others
UniRef100: UniRef100_Q6P1D7
UniRef90: UniRef90_Q6P1D7
UniRef50: UniRef50_Q8IY92
UniGene: Mm.29935
CCDS: CCDS37240.1

全选

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