| Type | Description |
|---|---|
| Definition | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:58:00 | TGFbeta receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2alpha-, and INPP4B-mediated phosphoinositide conversions. | 31913757 |
| 2019-12-07 11:28:00 | MiR-31 suppressed cell proliferation, migration, and invasion of osteosarcoma by targeting PIK3C2A expression. | 30468462 |
| 2019-10-05 10:37:00 | the identification of the first patients with PIK3C2A deficiency establishes a role for PIK3C2A in neurological and skeletal development, as well as vision, and growth and implicates loss-of-function PIK3C2A mutations as a potentially new cause of a cilia-associated disease. | 31034465 |
| 2019-09-21 12:22:00 | Study illustrates that the C-terminal PX-C2 module of PI3K-C2a plays an important role in membrane anchoring, with the C2 domain providing the primary site of membrane affinity, and suggests a possible role for Ca2+ in regulating PI3K-C2a activity through perturbation of C2 domain membrane interaction. | 30293811 |
| 2019-06-01 13:01:00 | PI3K-C2alpha and PI3K-C2beta play differential, indispensable roles in clathrin-mediated pinocytosis. | 30374841 |
| Type | IDs |
|---|---|
| Synonymous | CPK, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alpha |
| Gene |
UniProtKB-ID:
P3C2A_HUMAN,
B4DG55_HUMAN,
L7RRS0_HUMAN
UniprotKB:
O00443,
B4DG55,
L7RRS0
UniParc:
UPI00017A6E35,
UPI000013D6B3,
UPI0004EFFC6D
EMBL:
Y13367,
JX512454,
AK304262,
EU332862,
AC126389,
AC107956,
AK294416,
BC113658,
AC116533,
CH471064
Ensembl:
ENSG00000011405
KO:
hsa:5286
|
| Nucleutide sequences |
EMBL-CDS:
AAI13659.1,
ABY87551.1,
EAW68447.1,
BAG65126.1,
CAA73797.1,
BAG57666.1,
AGC09601.1
Ensembl_TRS:
ENST00000265970
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265970
RefSeq:
XP_016873413.1,
NP_001373799.1,
NP_001308309.1,
NP_001308307.1,
NP_002636.2
|
| Others |
UniRef100:
UniRef100_O00443,
UniRef100_B4DG55
UniRef90:
UniRef90_O00443,
UniRef90_L5L5Y4
UniRef50:
UniRef50_O00443,
UniRef50_H0WK36
UniGene:
Hs.175343
CCDS:
CCDS7824.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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