| Type | Description |
|---|---|
| Definition | RUN and FYVE domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:53:00 | RUFY3, a neuronally enriched protein, is essential for caspase-mediated degeneration of TRKA+ sensory axons in vitro and in vivo. Deletion of Rufy3 protects axons from degeneration, even in the presence of activated CASP3 . Dephosphorylation of RUFY3 at residue S34 appears required for axon degeneration. | 31221560 |
| 2018-12-22 10:08:00 | Rufy3 is a physiological adapter for Rap2 and activates Tiam2/STEF in glycoprotein M6A-regulated neuronal polarity and axon growth. | 29089386 |
| 2014-10-18 11:23:00 | We propose that Rufy3 may control mouse neuron axon development | 24720729 |
| 2010-01-21 00:00:00 | the putative Rap2 binding site of the RPIPx RUN domain interacts with the extended segment in a segment-swapping manner | 16928684 |
| Type | IDs |
|---|---|
| Synonymous | 2810428M05Rik, 6330416M07Rik, AW455998, AW538594, D5Bwg0860e, Ripx, Rpipx |
| Gene |
UniProtKB-ID:
RUFY3_MOUSE,
A0A0G2JFT8_MOUSE
UniprotKB:
Q9D394,
A0A0G2JFT8
UniParc:
UPI0000023175,
UPI00015DF1A5,
UPI0000D8AAEB,
UPI00019B221D,
UPI00001CE1B9
EMBL:
AK148795,
AK018184,
BC058259,
BC049127,
AC121541,
AK154941,
CT010404,
AK083242,
BC017648
Ensembl:
ENSMUSG00000029291
KO:
mmu:52822
|
| Nucleutide sequences |
EMBL-CDS:
BAB31113.1,
AAH17648.1,
BAE32941.1,
BAC38826.1,
AAH49127.1,
BAE28665.1,
CAJ18610.1,
AAH58259.1
Ensembl_TRS:
ENSMUST00000031229,
ENSMUST00000196686,
ENSMUST00000199312,
ENSMUST00000196894,
ENSMUST00000198965
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000143770,
ENSMUSP00000143209,
ENSMUSP00000143115,
ENSMUSP00000031229,
ENSMUSP00000143302
RefSeq:
NP_001276704.1,
NP_001346138.1,
NP_001276706.1,
XP_036021188.1,
XP_017176472.1,
XP_006535177.1,
XP_006535174.1,
XP_036021187.1,
XP_006535179.1,
XP_006535178.1,
NP_081806.1,
XP_006535175.1,
XP_006535172.1,
XP_036021186.1,
NP_001276703.1,
NP_001346137.1,
NP_001276705.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JFT8,
UniRef100_Q9D394
UniRef90:
UniRef90_Q7L099-4,
UniRef90_Q9D394
UniRef50:
UniRef50_Q9D394,
UniRef50_Q7L099-2
UniGene:
Mm.270469
CCDS:
CCDS80325.1,
CCDS19403.1,
CCDS80323.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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