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527 ATP6V0C

527

ATP6V0C

ATPase H+ transporting V0 subunit c

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATPase H+ transporting V0 subunit c

研究结论

Date Results Publications
2020-12-26 13:11:00 The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release. 32291285
2020-06-20 12:53:00 ATP6V0C enhances aerobic glycolysis and motility in Esophageal cancer cells. 31554233
2020-02-22 12:10:00 Study demonstrated that ATP6L is markedly overexpressed in the poorly differentiated colorectal cancer (CRC) tissues evidently located in the invasive front and metastatic foci. More importantly, in vitro and in vivo data demonstrated that ATP6L can induce the EMT program and promote tumor progression in CRC cells. 31840304
2018-07-21 10:40:00 Results found that the expression of ATP6V0C was higher in prostate cancer (PC) cell lines with high metastatic potential than that with low metastatic potential, indicating that ATP6V0C enhanced metastatic capacity in prostate cancer cells. Its silencing effectively suppressed the migration and invasion of PC cells through the inhibition of the function of V-ATPase, not through a LASS2/TMSG1-dependent manner. 29138865
2018-07-03 15:17:00 RBP2 could induce epithelial-mesenchymal transition in esophageal cancer cells and exert a greater effect on the expression of E-cadherin in lung squamous cells than in esophageal squamous cells. 26264242

名称对应

Type IDs
Synonymous ATP6C, ATP6L, ATPL, VATL, VPPC, Vma3
Gene
UniProtKB-ID: VATL_HUMAN
UniprotKB: P27449
UniParc: UPI0000041173
EMBL: CR541951, BC007759, CR541930, BC004537, BT007155, BC009290, M62762, BC007389
Ensembl: ENSG00000185883
KO: hsa:527
Nucleutide sequences
EMBL-CDS: CAG46749.1, AAH04537.1, AAH07759.1, AAP35819.1, AAH07389.1, CAG46728.1, AAH09290.1, AAA60039.1
Ensembl_TRS: ENST00000330398
Protein sequencees
Ensembl_PRO: ENSP00000329757
RefSeq: NP_001185498.1, NP_001685.1
Others
UniRef100: UniRef100_P27449
UniRef90: UniRef90_P27449
UniRef50: UniRef50_P27449
UniGene: Hs.389107
CCDS: CCDS10470.1

全选

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