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5267 SERPINA4

5267

SERPINA4

serpin family A member 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition serpin family A member 4

研究结论

Date Results Publications
2020-05-30 12:18:00 Low expression of kallistatin was associated with unfavourable prognosis and platinum resistance in high-grade serous (HGSOC). Overexpression of kallistatin significantly inhibited proliferation and metastasis, and enhanced platinum sensitivity and apoptosis in ovarian cancer cells. These findings demonstrate that kallistatin serves as a prognostic predictor and provide a potential therapeutic target for HGSOC 31884974
2019-06-08 12:31:00 patients with less severe excretory pancreatic insufficiency and lipid profile disorders had higher kallistatin level than the control group 29729163
2019-03-30 10:24:00 These findings provide, for the first time, evidence of a novel role of kallistatin in obesity and its associated comorbidities by limiting adipose tissue inflammation and oxidative stress 29679615
2018-12-01 11:27:00 Kallistatin levels may provide useful information regarding cardiovascular risk in women with polycystic ovary syndrome 28294594
2018-10-13 10:18:00 Kallistatin functions as an endogenous lymphangiogenesis inhibitor and has an important part in the lymphatic metastasis of gastric cancer.Kallistatin was reduced in the cancer tissue and plasma of gastric cancer patients. 29243194

名称对应

Type IDs
Synonymous KAL, KLST, KST, PI-4, PI4, kallistatin
Gene
UniProtKB-ID: KAIN_HUMAN, A0A024R6I9_HUMAN
UniprotKB: P29622, A0A024R6I9
UniParc: UPI000000CBEF
EMBL: HM005562, L28101, L19684, CH471061, BX248009, BC014992, BX248760
Ensembl: ENSG00000100665
KO: hsa:5267
Nucleutide sequences
EMBL-CDS: CAD66567.1, CAD62337.1, AAC41706.1, AAA59454.1, AAH14992.1, EAW81579.1, EAW81581.1, EAW81580.1, AEE61159.1
Gene_ORFName: hCG_22333
Ensembl_TRS: ENST00000298841, ENST00000557004, ENST00000555095
Protein sequencees
Ensembl_PRO: ENSP00000450838, ENSP00000298841, ENSP00000451172
RefSeq: NP_001275961.1, NP_001275962.1, NP_006206.2
Others
UniRef100: UniRef100_P29622
UniRef90: UniRef90_P29622
UniRef50: UniRef50_P29622
UniGene: Hs.719893
CCDS: CCDS9927.1

全选

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