| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor (GEF) 25 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-20 10:18:00 | In cultured neonatal cardiac fibroblasts, p63RhoGEF regulated the angiotensin II (Ang II)-dependent RhoA activation, the activation of the serum response factor, and the expression and secretion of CTGF. | 26392029 |
| 2014-12-27 11:13:00 | The Geft knockout mice develop normally and exhibit no discernable phenotype, suggesting Geft is dispensable for the development of the second heart field in mouse. | 22449701 |
| 2013-12-14 12:27:00 | Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Galpha(q/11)--p63RhoGEF--RhoA axis. | 23696743 |
| 2012-01-28 11:12:00 | GEFT regulation of lens differentiation and eye development occurs through a Rac1-dependent mechanism. | 21663592 |
| 2011-12-17 11:40:00 | Signaling through p63RhoGEF provides a novel mechanism for selective regulation of blood pressure. | 21885830 |
| Type | IDs |
|---|---|
| Synonymous | 2410008H17Rik, D10Ertd610e, GEFT |
| Gene |
UniProtKB-ID:
ARHGP_MOUSE,
G5E825_MOUSE,
A0A0R4J211_MOUSE
UniprotKB:
Q9CWR0,
G5E825,
A0A0R4J211
UniParc:
UPI000000365B,
UPI0001642879,
UPI00005AD215,
UPI000024DA4E
EMBL:
AK010452,
BC023367,
AF487515,
AK158684,
AC144852
Ensembl:
ENSMUSG00000019467
KO:
mmu:52666
|
| Nucleutide sequences |
EMBL-CDS:
AAO49464.1,
BAE34610.1,
BAB26951.1,
AAH23367.1
Ensembl_TRS:
ENSMUST00000019611,
ENSMUST00000167353
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019611,
ENSMUSP00000126339
RefSeq:
NP_001345486.1,
XP_006513944.1,
NP_001345487.1,
XP_006513942.1,
XP_030101037.1,
NP_082303.2,
NP_001159885.1
|
| Others |
UniRef100:
UniRef100_G5E825,
UniRef100_Q9CWR0,
UniRef100_A0A0R4J211
UniRef90:
UniRef90_Q9CWR0,
UniRef90_Q9CWR0-2
UniRef50:
UniRef50_Q86VW2
UniGene:
Mm.272230
CCDS:
CCDS48715.1,
CCDS24231.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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