Type | Description |
---|---|
Definition | SUZ12 polycomb repressive complex 2 subunit |
Date | Results | Publications |
---|---|---|
2020-02-08 10:58:00 | Here we show that CRISPR/Cas9-mediated inactivation of Suz12 cooperates with mutant JAK3 to drive T-cell transformation and T-cell acute lymphoblastic leukemia development | 31492675 |
2019-07-27 11:15:00 | SUZ12 binds to CpG islands and this stable recruitment to genomic loci is essential for correct H3K27 methylation patterns. | 29483650 |
2019-02-09 10:56:00 | Nsd1 is a key modulator of PRC2 function required for regulating the demarcation of genome-wide H3K27me2 and H3K27me3 domains in embryonic stem cells. | 29606589 |
2017-11-25 14:40:00 | we found that the miRNA biogenesis enzyme DICER was required for the binding of the PRC2 core components EZH2 and SUZ12, and for the presence of the PRC2-mediated histone modification H3K27me3 at many bivalent genes | 27150236 |
2017-10-28 11:29:00 | Biochemical as well as functional experiments revealed that Spt6 could compete for binding of the PRC2 methyltransferase Ezh2 to Suz12 and reduce PRC2 chromatin engagement. | 29033324 |
Type | IDs |
---|---|
Synonymous | 2610028O16Rik, AI195385, AU016842, AW536442, D11Ertd530e, mKIAA0160 |
Gene |
UniProtKB-ID:
SUZ12_MOUSE,
E9PW15_MOUSE
UniprotKB:
Q80U70,
E9PW15
UniParc:
UPI00001B2F55,
UPI0001AE8268
EMBL:
BC051099,
AK122213,
AL591113,
BC064461,
BC003922
Ensembl:
ENSMUSG00000017548
KO:
mmu:52615
|
Nucleutide sequences |
EMBL-CDS:
AAH03922.1,
AAH51099.1,
BAC65495.1,
AAH64461.1
Ensembl_TRS:
ENSMUST00000017692,
ENSMUST00000163272
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000017692,
ENSMUSP00000126932
RefSeq:
NP_954666.1,
NP_001156490.1
|
Others |
UniRef100:
UniRef100_Q80U70,
UniRef100_E9PW15
UniRef90:
UniRef90_Q80U70,
UniRef90_J3QQW9
UniRef50:
UniRef50_Q80U70,
UniRef50_Q6DC03
UniGene:
Mm.283410,
Mm.473315
CCDS:
CCDS25125.1
|
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Refseq |
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